Jump to content
Main menu
Main menu
move to sidebar
hide
Navigation
Main page
Recent changes
Random page
Help about MediaWiki
Special pages
Niidae Wiki
Search
Search
Appearance
Create account
Log in
Personal tools
Create account
Log in
Pages for logged out editors
learn more
Contributions
Talk
Editing
Orthostatic hypotension
(section)
Page
Discussion
English
Read
Edit
View history
Tools
Tools
move to sidebar
hide
Actions
Read
Edit
View history
General
What links here
Related changes
Page information
Appearance
move to sidebar
hide
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Causes== Some causes of orthostatic hypotension include [[Neurodegeneration|neurodegenerative disorders]], [[hypovolemia|low blood volume]] (e.g. caused by [[dehydration]], [[bleeding]], or the use of [[diuretic]]s), drugs that cause [[vasodilation]], other types of drugs (notably, [[narcotic]]s and [[marijuana]]), discontinuation of [[vasoconstrictor]]s, prolonged [[bed rest]] (immobility), significant recent weight loss, [[anemia]],<ref>{{cite web|title=What Causes Hypotension? - |url=https://www.nhlbi.nih.gov/health/health-topics/topics/hyp/causes|work = National Heart, Lung, and Blood Institute (NHLBI) | publisher = U.S. National Institutes of Health |access-date=27 March 2017 }}</ref> [[Vitamin B12 deficiency|vitamin B<sub>12</sub> deficiency]], or recent [[bariatric surgery]].<ref>{{cite journal | vauthors = Christou GA, Kiortsis DN | title = The effects of body weight status on orthostatic intolerance and predisposition to noncardiac syncope | journal = Obesity Reviews | volume = 18 | issue = 3 | pages = 370β379 | date = March 2017 | pmid = 28112481 | doi = 10.1111/obr.12501 | s2cid = 46498296 }}</ref> ===Medication=== [[File:Tetrahydrocannabinol.svg|thumb|160 px|Tetrahydrocannabinol]] Orthostatic hypotension can be a side effect of certain [[antidepressants]], such as [[tricyclic antidepressant|tricyclics]]<ref name=pmid16290952>{{cite journal | vauthors = Jiang W, Davidson JR | title = Antidepressant therapy in patients with ischemic heart disease | journal = American Heart Journal | volume = 150 | issue = 5 | pages = 871β881 | date = November 2005 | pmid = 16290952 | doi = 10.1016/j.ahj.2005.01.041 }}</ref> or [[monoamine oxidase inhibitor]]s (MAOIs)<ref name=pmid12412837>{{cite journal | vauthors = Jones RT | title = Cardiovascular system effects of marijuana | journal = Journal of Clinical Pharmacology | volume = 42 | issue = S1 | pages = 58Sβ63S | date = November 2002 | pmid = 12412837 | doi = 10.1002/j.1552-4604.2002.tb06004.x | s2cid = 12193532 }}</ref> Alcohol can potentiate orthostatic hypotension to the point of [[syncope (medicine)|syncope]].<ref name=pmid10653831>{{cite journal | vauthors = Narkiewicz K, Cooley RL, Somers VK | title = Alcohol potentiates orthostatic hypotension : implications for alcohol-related syncope | journal = Circulation | volume = 101 | issue = 4 | pages = 398β402 | date = February 2000 | pmid = 10653831 | doi = 10.1161/01.CIR.101.4.398 | doi-access = free }}</ref> Orthostatic hypotension can also be a side effect of [[alpha-1 blocker]]s (alpha<sub>1</sub> adrenergic blocking agents). Alpha<sub>1</sub> blockers inhibit vasoconstriction normally initiated by the [[baroreceptor reflex]] upon postural change and the subsequent drop in pressure.<ref>{{cite web | vauthors = Shea MJ, Thompson AD | title = Orthostatic Hypotension | url = https://www.msdmanuals.com/professional/cardiovascular-disorders/symptoms-of-cardiovascular-disorders/orthostatic-hypotension | work = [[Merck Manual]] }}</ref> Other [[antihypertensive drug|antihypertensive medications]] may also cause orthostatic hypotension, in addition to [[anticholinergic]]s, [[dopaminergic]] drugs, [[opiates]] and [[psychoactive drug|psychoactive medications]].<ref name="AAFP Kim" /> ===Other factors=== Patients prone to orthostatic hypotension are the elderly, ''[[post partum]]'' mothers, and those having been on bed rest. People with anorexia nervosa and [[bulimia nervosa]] often develop orthostatic hypotension as a common side effect. Consuming alcohol may also lead to orthostatic hypotension due to its dehydrating effects.{{citation needed | date=April 2015}}
Summary:
Please note that all contributions to Niidae Wiki may be edited, altered, or removed by other contributors. If you do not want your writing to be edited mercilessly, then do not submit it here.
You are also promising us that you wrote this yourself, or copied it from a public domain or similar free resource (see
Encyclopedia:Copyrights
for details).
Do not submit copyrighted work without permission!
Cancel
Editing help
(opens in new window)
Search
Search
Editing
Orthostatic hypotension
(section)
Add topic