Editing Nerve (section)

==Development==
Nerve growth normally ends in adolescence but can be re-stimulated with a molecular mechanism known as "[[notch signaling]]".<ref>[https://www.sciencedaily.com/releases/1999/10/991022005127.htm Yale Study Shows Way To Re-Stimulate Brain Cell Growth ScienceDaily] {{webarchive|url=https://web.archive.org/web/20170707062502/https://www.sciencedaily.com/releases/1999/10/991022005127.htm |date=2017-07-07 }} (Oct. 22, 1999) — Results Could Boost Understanding Of Alzheimer's, Other Brain Disorders</ref> If the axons of a [[neuron]] are damaged, as long as [[Soma (biology)|the cell body]] of the neuron is not damaged, the axons can regenerate and remake the synaptic connections with neurons with the help of [[guidepost cells]]. This is also referred to as [[neuroregeneration]].<ref>{{cite journal |last=Kunik |first=D |title=Laser-based single-axon transection for high-content axon injury and regeneration studies |journal=PLOS ONE |year=2011 |volume=6 |issue=11 |pages=e26832 |doi=10.1371/journal.pone.0026832 |pmid=22073205 |pmc=3206876|bibcode=2011PLoSO...626832K |doi-access=free }}</ref> The nerve begins the process by destroying the nerve [[distal]] to the site of injury allowing Schwann cells, basal lamina, and the neurilemma near the injury to begin producing a regeneration tube. Nerve growth factors are produced causing many nerve sprouts to bud.  When one of the growth processes finds the regeneration tube, it begins to grow rapidly towards its original destination guided the entire time by the regeneration tube. Nerve regeneration is very slow and can take up to several months to complete. While this process does repair some nerves, there will still be some functional deficit as the repairs are not perfect.<ref>{{cite web|url=http://www.medscape.com/viewarticle/480071_5|title=Pathophysiology of Peripheral Nerve Injury: A Brief Review: Nerve Regeneration|last1=Burnett |last2=Zager|first1=Mark |first2=Eric|publisher=Medscape|work=Medscape Article|access-date=2011-10-26|url-status=live|archive-url=https://web.archive.org/web/20111031061528/http://www.medscape.com/viewarticle/480071_5|archive-date=2011-10-31}}</ref>