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=== Mood and memory effects === Psychological symptoms are often reported but they are not specific to menopause and can be caused by other factors.<ref name=":2">{{Cite journal |last1=Hogervorst |first1=Eef |last2=Craig |first2=Jen |last3=O'Donnell |first3=Emma |date=2022-05-01 |title=Cognition and mental health in menopause: A review |url=https://www.sciencedirect.com/science/article/pii/S1521693421001644 |journal=Best Practice & Research Clinical Obstetrics & Gynaecology |series=Menopause Management |language=en |volume=81 |pages=69–84 |doi=10.1016/j.bpobgyn.2021.10.009 |issn=1521-6934 |pmid=34969617|s2cid=244805452 }}</ref><ref name=":1">{{Cite journal |last1=Kilpi |first1=Fanny |last2=Soares |first2=Ana Luiza G. |last3=Fraser |first3=Abigail |last4=Nelson |first4=Scott M. |last5=Sattar |first5=Naveed |last6=Fallon |first6=Sean James |last7=Tilling |first7=Kate |last8=Lawlor |first8=Deborah A. |date=14 August 2020 |title=Changes in six domains of cognitive function with reproductive and chronological ageing and sex hormones: a longitudinal study in 2411 UK mid-life women |journal=BMC Women's Health |language=en |volume=20 |issue=1 |page=177 |doi=10.1186/s12905-020-01040-3 |issn=1472-6874 |pmc=7427852 |pmid=32795281 |doi-access=free }}</ref> They include [[anxiety]], poor memory, inability to concentrate, depressive mood, [[irritability]], [[mood swing]]s, and less [[Libido|interest in sexual activity]].<ref name="Hoffman20122" /><ref name="Llaneza2">{{cite journal |vauthors=Llaneza P, García-Portilla MP, Llaneza-Suárez D, Armott B, Pérez-López FR |date=February 2012 |title=Depressive disorders and the menopause transition |journal=Maturitas |volume=71 |issue=2 |pages=120–30 |doi=10.1016/j.maturitas.2011.11.017 |pmid=22196311}}</ref><ref name="NIH2013Sym" /> [[Postmenopausal confusion|Menopause-related cognitive impairment]] can be confused with the [[mild cognitive impairment]] that precedes [[dementia]].<ref>{{Cite book |title=Managing the Menopause: 21st Century Solutions |vauthors=Panay N, Briggs P, Kovacs G |date=20 August 2015 |publisher=Cambridge University Press |isbn=9781316352717 |chapter=Memory and Mood in the Menopause |chapter-url=https://books.google.com/books?id=UZ9rCgAAQBAJ&pg=PA91}}</ref> There is evidence of small decreases in verbal memory, on average, which may be caused by the effects of declining estrogen levels on the brain,<ref name=":02">{{Cite book |url=https://books.google.com/books?id=JtBJDwAAQBAJ&pg=PA38 |title=Pre-Menopause, Menopause and Beyond: Volume 5: Frontiers in Gynecological Endocrinology |vauthors=Birkhaeuser M, Genazzani AR |date=30 January 2018 |publisher=Springer |isbn=9783319635408 |pages=38–39}}</ref> or perhaps by reduced blood flow to the brain during [[hot flash]]es.<ref>{{Cite book |url=https://books.google.com/books?id=xTExDwAAQBAJ |title=Current Medical Diagnosis and Treatment 2018, 57th Edition |vauthors=Papadakis MA, McPhee SJ, Rabow MW |date=11 September 2017 |publisher=McGraw Hill Professional |isbn=9781259861499 |pages=1212}}</ref> However, these tend to resolve for most women during the postmenopause. Subjective reports of memory and concentration problems are associated with several factors, such as lack of sleep, and stress.<ref name=":1" /><ref name=":2" />
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