Editing Lymph node (section)

===Subdivisions{{Anchor|cortex|medulla}}===
[[File:Dark, light, mantle and marginal zones of a secondary follicle.png|230px|thumb|Histology of a normal [[lymphoid follicle]], showing dark, light, mantle and marginal zones]]
A lymph node is divided into compartments called ''nodules'' (or lobules), each consisting of a region of cortex with combined follicle B cells, a paracortex of T cells, and a part of the nodule in the medulla.<ref name="Willard-Mack" /> The substance of a lymph node is divided into the outer ''cortex'' and the inner ''medulla''.<ref name=Wheaters2013 /> The cortex of a lymph node is the outer portion of the node, underneath the capsule and the subcapsular sinus.<ref name=Willard-Mack/> It has an outer part and a deeper part known as the ''paracortex''.<ref name="Willard-Mack">{{cite journal | vauthors = Willard-Mack CL | title = Normal structure, function, and histology of lymph nodes | journal = Toxicologic Pathology | volume = 34 | issue = 5 | pages = 409–24 | date = 25 June 2016 | pmid = 17067937 | doi = 10.1080/01926230600867727 | doi-access = free }}</ref> The outer cortex consists of groups of mainly inactivated B cells called follicles.<ref name="Grays2016" /> When activated, these may develop into what is called a [[germinal centre]].<ref name="Grays2016" /> The deeper paracortex mainly consists of the [[T cell]]s.<ref name="Grays2016" /> Here the T-cells mainly interact with [[dendritic cell]]s, and the reticular network is dense.<ref name="katakai">{{cite journal | vauthors = Katakai T, Hara T, Lee JH, Gonda H, Sugai M, Shimizu A | title = A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells | journal = International Immunology | volume = 16 | issue = 8 | pages = 1133–42 | date = August 2004 | pmid = 15237106 | doi = 10.1093/intimm/dxh113 | doi-access = free }}</ref>

The medulla contains large blood vessels, sinuses and medullary cords that contain antibody-secreting plasma cells. There are fewer cells in the medulla.<ref name="Grays2016" />

The '''medullary cords''' are cords of lymphatic tissue, and include [[plasma cell]]s, macrophages, and B cells.