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== Commercial use == [[Impossible Foods]] asked the American [[Food and Drug Administration|FDA]] for their approval to use recombinant soy leghemoglobin made by ''[[Pichia pastoris]]'' in [[Meat alternative|meat alternatives]] as an [[Functional analog (chemistry)|analog]] of meat-derived [[hemoglobin]].<ref>{{Cite web |title=GRAS Notice 540 |url=https://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=540 |website=www.accessdata.fda.gov |access-date=2018-01-21 |archive-date=2017-06-30 |archive-url=https://web.archive.org/web/20170630052957/https://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=540 |url-status=dead }}</ref><ref>{{Cite web |url=https://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=737 |archive-url=https://web.archive.org/web/20180504172520/https://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices&id=737 |url-status=dead |archive-date=May 4, 2018 |title=GRAS Notice 737 |website=www.accessdata.fda.gov |access-date=2018-08-22 }}</ref> Approval from the FDA came in July 2019,<ref>{{Cite web |url=https://www.cnbc.com/2019/07/31/beyond-meats-competitor-impossible-foods-gets-fda-approval.html |title=Beyond Meat's competitor Impossible Foods plans to launch in grocery stores in September after getting FDA approval |date=31 July 2019 |website=CNBC |access-date=31 July 2019}}</ref> was challenged,{{Efn|filed by the non-profit advocacy organization Center for Food Safety}} and later upheld, on May 3, 2021, by a San Francisco federal appeals court.<ref>{{cite web |author=Justine Calma |url=https://www.theverge.com/2021/5/3/22418036/impossible-foods-legal-battle-key-ingredient-heme-fda |date=May 3, 2021 |title=Impossible Foods clears legal battle over the ingredient that makes its meat 'bleed' |website=theverge.com |url-status=live |archive-url=https://web.archive.org/web/20210507190036/https://www.theverge.com/2021/5/3/22418036/impossible-foods-legal-battle-key-ingredient-heme-fda |archive-date=2021-05-07}}</ref><ref>{{cite web |author=Sally Ho |date=May 6, 2021 |url=https://www.greenqueen.com.hk/impossible-foods-wins-legal-battle-over-heme-ingredient-powering-bleeding-plant-based-burger/ |title=Impossible Foods Wins Legal Battle Over Heme Ingredient Powering 'Bleeding' Plant-Based Burger |website=greenqueen.com.hk |url-status=live |archive-url=https://web.archive.org/web/20210506070157/https://www.greenqueen.com.hk/impossible-foods-wins-legal-battle-over-heme-ingredient-powering-bleeding-plant-based-burger/ |archive-date=2021-05-06}}</ref> It is currently being used in their products to mimic the color, taste, and texture of meat.<ref>{{cite web |last=Bandoim |first=L. |date=December 20, 2019 |title=What The FDA's Decision About Soy Leghemoglobin Means For Impossible Burger |website=[[Forbes]] |url=https://www.forbes.com/sites/lanabandoim/2019/12/20/what-the-fdas-decision-about-soy-leghemoglobin-means-for-impossible-burger/#5e0a8c7457f6 |access-date=March 4, 2020}}</ref>
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