Editing Keloid (section)

== Genetics ==
[[File:The Surgical history of the naval war between Japan and China - during 1894-95; translated from the original Japanese report (1900) (14595050100).jpg|thumb|Japanese sailor with keloid scarring during the [[First Sino-Japanese War]]. People of Asian descent are among the groups more likely to develop keloid scars.]]
People who have ancestry from [[Sub-Saharan Africa]], Asia, or [[Latin America]] are more likely to develop a keloid. Among [[Han Chinese|ethnic Chinese]] in Asia, the keloid is the most common skin condition. In the United States, keloids are more common in African Americans and Hispanic Americans than European Americans. Those who have a family history of keloids are also susceptible since about 1/3 of people who get keloids have a first-degree blood relative (mother, father, sister, brother, or child) who also gets keloids. This family trait is most common in people of African and/or Asian descent.

The development of keloids among twins also lends credibility to the existence of a genetic susceptibility to develop keloids. Marneros et al. (1) reported four sets of identical twins with keloids; Ramakrishnan et al.<ref name="pmid4813760">{{cite journal | vauthors = Ramakrishnan KM, Thomas KP, Sundararajan CR | title = Study of 1,000 patients with keloids in South India | journal = Plastic and Reconstructive Surgery | volume = 53 | issue = 3 | pages = 276–280 | date = March 1974 | pmid = 4813760 | doi = 10.1097/00006534-197403000-00004 }}</ref> also described a pair of twins who developed keloids at the same time after vaccination. Case series have reported clinically severe forms of keloids in individuals with positive family history and black African ethnic origin.