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=== Analytical methods === HMX enters the environment through air, water, and soil because it is widely used in military and civil applications. At present, reverse-phase HPLC and more sensitive LC-MS methods have been developed to accurately quantify the concentration of HMX in a variety of matrices in environmental assessments.<ref>{{Cite journal|last1=Liu|first1=Jun|last2=Severt|first2=Scott A.|last3=Pan|first3=Xiaoping|last4=Smith|first4=Philip N.|last5=McMurry|first5=Scott T.|last6=Cobb|first6=George P.|date=2007-02-15|title=Development of an extraction and cleanup procedure for a liquid chromatographic–mass spectrometric method to analyze octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine in eggs|journal=Talanta|volume=71|issue=2|pages=627–631|doi=10.1016/j.talanta.2006.05.007|pmid=19071351}}</ref><ref>{{Cite journal|last1=Pan|first1=Xiaoping|last2=Zhang|first2=Baohong|last3=Tian|first3=Kang|last4=Jones|first4=Lindsey E.|last5=Liu|first5=Jun|last6=Anderson|first6=Todd A.|last7=Wang|first7=Jia-Sheng|last8=Cobb|first8=George P.|date=2006-07-30|title=Liquid chromatography/electrospray ionization tandem mass spectrometry analysis of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX)|journal=Rapid Communications in Mass Spectrometry|language=en|volume=20|issue=14|pages=2222–2226|doi=10.1002/rcm.2576|pmid=1679187|bibcode=2006RCMS...20.2222P |issn=1097-0231}}</ref>
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