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==== Synthesis ==== {{See also|Synthesis of precious metals}} The possible production of gold from a more common element, such as [[lead]], has long been a subject of human inquiry, and the ancient and medieval discipline of [[alchemy]] often focused on it; however, the transmutation of the chemical elements did not become possible until the understanding of [[nuclear physics]] in the 20th century. The first synthesis of gold was conducted by Japanese physicist [[Hantaro Nagaoka]], who synthesized gold from [[mercury (element)|mercury]] in 1924 by neutron bombardment.<ref>{{Cite journal |last1=Miethe |first1=A. |title=Der Zerfall des Quecksilberatoms |doi=10.1007/BF01505547 |journal=Die Naturwissenschaften |volume=12 |issue=29 |pages=597β598 |year=1924 |bibcode=1924NW.....12..597M|s2cid=35613814 }}</ref> An American team, working without knowledge of Nagaoka's prior study, conducted the same experiment in 1941, achieving the same result and showing that the [[isotopes of gold]] produced by it were all [[radioactive]].<ref>{{cite journal |last1=Sherr |first1=R. |first2=K. T. |last2=Bainbridge |first3=H. H. |last3=Anderson |name-list-style=amp |title=Transmutation of Mercury by Fast Neutrons |date=1941 |journal=[[Physical Review]] |volume=60 |issue=7 |pages=473β479 |doi=10.1103/PhysRev.60.473 |bibcode=1941PhRv...60..473S}}</ref> In 1980, [[Glenn T. Seaborg|Glenn Seaborg]] transmuted several thousand atoms of bismuth into gold at the Lawrence Berkeley Laboratory.<ref>{{Cite journal|last1=Aleklett |first1=K.|last2=Morrissey |first2=D.|last3=Loveland |first3=W.|last4=McGaughey |first4=P.|last5=Seaborg |first5=G.|year=1981|title=Energy dependence of <sup>209</sup>Bi fragmentation in relativistic nuclear collisions|journal=[[Physical Review C]]|volume=23 |issue=3 |page=1044|bibcode=1981PhRvC..23.1044A|doi=10.1103/PhysRevC.23.1044}}</ref><ref>{{cite news |url=https://www.telegraph.co.uk/education/4791069/The-Philosophers-Stone.html |newspaper=[[The Daily Telegraph]] |first=Robert |last=Matthews |title=The Philosopher's Stone |date=2 December 2001 |access-date=22 September 2020 }}</ref> Gold can be manufactured in a nuclear reactor, but doing so is highly impractical and would cost far more than the value of the gold that is produced.<ref>{{cite book |last1=Shipman |first1=James |last2=Wilson |first2=Jerry D. |last3=Higgins |first3=Charles A. |title=An Introduction to Physical Science |date=2012 |publisher=Cengage Learning |isbn=978-1-133-70949-7 |page=273 |edition=13th}}</ref>
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