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==Health== A 2024 UK study found a life expectancy of 13.1 years for the breed compared to an average of 12.7 for purebreeds and 12 for [[Mongrel|crossbreeds]].{{r|life}} A 2024 Italian study found a life expectancy of 10 years for the breed compared to 10 years overall.<ref>{{cite journal | last=Roccaro | first=Mariana | last2=Salini | first2=Romolo | last3=Pietra | first3=Marco | last4=Sgorbini | first4=Micaela | last5=Gori | first5=Eleonora | last6=Dondi | first6=Maurizio | last7=Crisi | first7=Paolo E. | last8=Conte | first8=Annamaria | last9=Dalla Villa | first9=Paolo | last10=Podaliri | first10=Michele | last11=Ciaramella | first11=Paolo | last12=Di Palma | first12=Cristina | last13=Passantino | first13=Annamaria | last14=Porciello | first14=Francesco | last15=Gianella | first15=Paola | last16=Guglielmini | first16=Carlo | last17=Alborali | first17=Giovanni L. | last18=Rota Nodari | first18=Sara | last19=Sabatelli | first19=Sonia | last20=Peli | first20=Angelo | title=Factors related to longevity and mortality of dogs in Italy | journal=Preventive Veterinary Medicine | volume=225 | date=2024 | doi=10.1016/j.prevetmed.2024.106155 | page=106155| doi-access=free | hdl=11585/961937 | hdl-access=free }}</ref> Dogs, both pedigree and cross breeds, can be affected with genetic problems.{{r|KChealth}} Those known to sometimes occur in English Setters can include congenital [[Deaf animal|deafness]], which was reported as affecting 12.4 percent of the 701 English Setters tested by the [[Louisiana State University]] in 2010.{{r|Deaf}} As at 2013, there has not been any detailed research on this condition undertaken in the UK;{{r|ESAdeaf}} [[autoimmune thyroiditis]], which was shown to affect 26.2 percent of 747 English Setters examined between January 1974 until December 2012 in an [[Orthopedic Foundation for Animals]] listing;{{r|OFFA}} canine [[Hypothyroidism in dogs|hypothyroidism]];{{r|ESAhypothyroid}} [[elbow dysplasia]]; and allergies, which can include some sensitivity to certain food ingredients and also skin conditions, are known to occur.{{r|ESAskin}}{{sfnp|Stead|2013|p=8|ps=none}} The breed is predisposed to atopic dermatitis.<ref>{{cite book | last=Rhodes | first=Karen Helton | last2=Werner | first2=Alexander H. | title=Blackwell's Five-Minute Veterinary Consult Clinical Companion | publisher=Wiley-Blackwell | publication-place=Ames, Iowa | date=2011-01-25 | isbn=978-0-8138-1596-1 | page=94}}</ref>
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