Editing Dolly (sheep) (section)

== Death ==
On 14 February 2003, Dolly was [[Animal euthanasia|euthanised]] because she had a progressive lung disease and severe arthritis.<ref name=final_illness>[http://www.roslin.ac.uk/publicInterest/DollyFinalIilness.php Dolly's final illness] {{webarchive|url=https://web.archive.org/web/20080227144956/http://www.roslin.ac.uk/publicInterest/DollyFinalIilness.php |date=27 February 2008 }} Roslin Institute, Accessed 21 February 2008 {{Webarchive|url=https://web.archive.org/web/20121030120853/http://www.roslin.ac.uk/publicInterest/DollyFinalIilness.php |date=30 October 2012 }}</ref> A [[Finnish Dorset sheep|Finn Dorset]] such as Dolly has a life expectancy of around 11 to 12 years, but Dolly lived 6.5 years. A post-mortem examination showed she had a form of lung cancer called [[ovine pulmonary adenocarcinoma]], also known as Jaagsiekte,<ref>Bridget M. Kuehn [http://www.avma.org/onlnews/javma/apr03/030415f.asp Goodbye, Dolly; first cloned sheep dies at six years old] {{webarchive |url=https://web.archive.org/web/20091004231844/http://www.avma.org/onlnews/javma/apr03/030415f.asp |date=4 October 2009 }} American Veterinary Medical Association, 15 April 2003</ref> which is a fairly common disease of sheep and is caused by the [[retrovirus]] [[JSRV]].<ref>{{Cite journal |author=Palmarini M |title=A Veterinary Twist on Pathogen Biology |journal=PLOS Pathog. |volume=3 |issue=2 |pages=e12 |date=2007 |pmid=17319740 |doi=10.1371/journal.ppat.0030012 |pmc=1803002 |doi-access=free }}</ref> Roslin scientists stated that they did not think there was a connection with Dolly being a clone, and that other sheep in the same flock had died of the same disease.<ref name=final_illness/> Such lung diseases are a particular danger for sheep kept indoors, and Dolly had to sleep inside for security reasons.<ref>{{Cite news|url=https://www.nytimes.com/2003/02/15/world/first-mammal-clone-dies-dolly-made-science-history.html|title=First Mammal Clone Dies; Dolly Made Science History|first=Gina|last=Kolata|newspaper=The New York Times|date=15 February 2003|access-date=8 May 2021|archive-date=26 February 2023|archive-url=https://web.archive.org/web/20230226163558/https://www.nytimes.com/2003/02/15/world/first-mammal-clone-dies-dolly-made-science-history.html|url-status=live}}</ref>

Some in the press speculated that a contributing factor to Dolly's death was that she could have been born with a genetic age of six years, the same age as the sheep from which she was cloned.<ref name=age/> One basis for this idea was the finding that Dolly's [[telomeres]] were short, which is typically a result of the [[aging]] process.<ref>{{Cite journal|author=Shiels PG|author2=Kind AJ|author3=Campbell KH|title=Analysis of telomere length in Dolly, a sheep derived by nuclear transfer |journal=Cloning |volume=1 |issue=2 |pages=119–25 |date=1999 |pmid=16218837 | doi = 10.1089/15204559950020003|display-authors=etal}}</ref><ref>{{Cite journal|author=Shiels PG|author2=Kind AJ|author3=Campbell KH|title=Analysis of telomere lengths in cloned sheep |journal=Nature |volume=399 |issue=6734 |pages=316–7 |date=1999 |pmid=10360570 | doi = 10.1038/20580|bibcode = 1999Natur.399..316H |s2cid=4380715|display-authors=etal}}</ref> The Roslin Institute stated that intensive health screening did not reveal any abnormalities in Dolly that could have come from advanced aging.<ref name=age>[http://www.roslin.ed.ac.uk/public-interest/dolly-the-sheep/a-life-of-dolly/ Was Dolly already 'old' at birth?] {{Webarchive|url=https://web.archive.org/web/20110528165730/http://www.roslin.ed.ac.uk/public-interest/dolly-the-sheep/a-life-of-dolly/ |date=28 May 2011 }} Roslin Institute, Accessed 4 April 2010</ref>

In 2016, scientists reported no defects in thirteen cloned sheep, including four from the same cell line as Dolly. The first study to review the long-term health outcomes of cloning, the authors found no evidence of late-onset, non-communicable diseases other than some minor examples of osteoarthritis and concluded "We could find no evidence, therefore, of a detrimental long-term effect of cloning by SCNT on the health of aged offspring among our cohort."<ref>{{cite journal|last1=Sinclair|first1=K. D.|last2=Corr|first2=S. A.|last3=Gutierrez|first3=C. G.|last4=Fisher|first4=P. A.|last5=Lee|first5=J.-H.|last6=Rathbone|first6=A. J.|last7=Choi|first7=I.|last8=Campbell|first8=K. H. S.|last9=Gardner|first9=D. S.|title=Healthy ageing of cloned sheep|journal=Nature Communications|volume=7|pages=12359|language=en|doi=10.1038/ncomms12359|pmid=27459299|pmc=4963533|date=26 July 2016|bibcode=2016NatCo...712359S}}</ref><ref>{{cite news|last1=Klein|first1=Joanna|title=Dolly the Sheep's Fellow Clones, Enjoying Their Golden Years|url=https://www.nytimes.com/2016/07/27/science/dolly-the-sheep-clones.html|access-date=27 July 2016|work=The New York Times|date=26 July 2016|archive-url=https://web.archive.org/web/20160729224740/http://www.nytimes.com/2016/07/27/science/dolly-the-sheep-clones.html|archive-date=29 July 2016|url-status=live}}</ref>

After her death Dolly's body was preserved via taxidermy and is currently on display at the [[National Museum of Scotland]] in Edinburgh.<ref name=BBC2023>{{cite news |date=24 December 2023 |title=Dolly the Sheep's fleece donated to museum |url=https://www.bbc.co.uk/news/uk-scotland-67810915 |work=BBC News |access-date=24 December 2023 |archive-date=24 December 2023 |archive-url=https://web.archive.org/web/20231224101135/https://www.bbc.co.uk/news/uk-scotland-67810915 |url-status=live }}</ref>