Editing Dendritic cell (section)

===In blood===
The blood DCs are typically identified and enumerated in [[flow cytometry]]. Three types of DCs have been defined in human blood: the CD1c+ myeloid DCs, the [[CD141]]+ myeloid DCs and the [[CD303]]+ plasmacytoid DCs. This represents the nomenclature proposed by the nomenclature committee of the [[International Union of Immunological Societies]].<ref>{{Cite journal | doi = 10.1182/blood-2010-02-258558 | pmid=20628149| year=2010| last1=Ziegler-Heitbrock| first1=L| title=Nomenclature of monocytes and dendritic cells in blood| journal=Blood| volume=116| issue=16| pages=e74–80| last2=Ancuta| first2=P| last3=Crowe| first3=S| last4=Dalod| first4=M| last5=Grau| first5=V| last6=Hart| first6=D. N.| last7=Leenen| first7=P. J.| last8=Liu| first8=Y. J.| last9=MacPherson| first9=G| last10=Randolph| first10=G. J.| last11=Scherberich| first11=J| last12=Schmitz| first12=J| last13=Shortman| first13=K| last14=Sozzani| first14=S| last15=Strobl| first15=H| last16=Zembala| first16=M| last17=Austyn| first17=J. M.| last18=Lutz| first18=M. B.| hdl=11379/41075| s2cid=1570404| url=https://iris.unibs.it/bitstream/11379/41075/1/Ziegler%20Blood%202010.pdf| hdl-access=free}}</ref>
Dendritic cells that circulate in blood do not have all the typical features of their counterparts in tissue, i.e. they are less mature and have no dendrites. Still, they can perform complex functions including chemokine-production (in CD1c+ myeloid DCs), [[cross-presentation]] (in CD141+ myeloid DCs), and IFNalpha production (in CD303+ plasmacytoid DCs).