Editing Daria (section)

===Supporting===
* Brittany Taylor (voiced by Lisa Kathleen Collins) is Lawndale High's ditzy cheerleader and Kevin's girlfriend.
* Kevin Thompson (voiced by [[Marc Thompson (voice actor)|Marc Thompson]]) is Lawndale High's quarterback and Brittany's similarly ditzy boyfriend.
* Trent Lane (voiced by Alvaro J. Gonzalez) is Jane's brother and Daria's initial love interest.
* Jodie Landon (voiced by Jessica Cydnee Jackson) is Lawndale High's black school president who is one of the few competent students.
* Michael “Mack” Jordan MacKenzie (voiced by Delon Ferdinand (early season 1), Paul Williams (remainder of season 1 and season 2), Kevin Daniels (season 3) and Amir Williams (seasons 4 and 5)) is Jodie's boyfriend and the Lawndale High football team's captain.
* Sandi Griffin (voiced by Lisa Kathleen Collins) is the snobby president of The Fashion Club.
* Tiffany Blum-Deckler (voiced by Ashley Albert) is the only non-white member of The Fashion Club who is known for her monotonous voice and lack of intelligence.
* Stacy Rowe (voiced by Jessica Zaino (early season 1) and [[Sarah Drew]] (remainder of the series run)) is the anxiety-prone secretary of The Fashion Club.
* Charles “Upchuck” Ruttheimer III (voiced by Marc Thompson (season 1) and Geoffrey Arend (season 2 to 5)), an obnoxious flirty student at Lawndale High.
* Andrea (voiced by Susie Lewis Lynn (season 1 to 3) and Lisa Kathleen Collins (season 4 and 5)) is a goth student at Lawndale High.
* Joey (voiced by [[Geoffrey Arend]] in "The Invitation" and Steven Huppert for the remainder of the series), Jeffy (voiced by Tim Novikoff) and Jamie (voiced by Marc Thompson) are three nearly interchangeable high-school students and members of the school's football team who constantly compete for Quinn's affection.
* Tom Sloane (season 4-5; guest season 3) (voiced by Russell Hankin) is a love interest of Jane and later Daria.
* Mr. Timothy O'Neill (voiced by Marc Thompson) is an overly-sentimental English teacher.
* Ms. Angela Li (voiced by Nora Laudani) is the corrupt, autocratic Asian school principal of Lawndale High.
* Mr. Anthony DeMartino (voiced by Marc Thompson) is an anger-prone history teacher who dislikes most of his students.
* Ms. Janet Barch (voiced by Ashley Albert) is a misandrist divorcee science teacher.
* Mrs. Diane Bennett (voiced by Amy Bennett) is an overly-enthusiastic economics teacher.
* Ms. Claire Defoe (voiced by Nicole Carin in seasons 1–2 and Danielle Carin for the remainder of the series) is an art teacher.