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=== Air pollution === [[Air pollution]], both [[Household air pollution|indoor]] and outdoor, is responsible for roughly 28% of deaths from CAD. This varies by region: In highly developed areas, this is approximately 10%, whereas in Southern, East and West Africa, and [[South Asia]], approximately 40% of deaths from CAD can be attributed to unhealthy air.<ref name="HEI_2024_p3-4">{{Cite book |last1=Health Effects Institute |author-link1=Health Effects Institute |url=https://www.stateofglobalair.org/resources/report/state-global-air-report-2024 |title=State of Global Air Report 2024: A Special Report on Global Exposure to Air Pollution and its Health Impacts with a Focus on Children's Health. |last2=Institute for Health Metrics and Evaluation |author-link2=Institute for Health Metrics and Evaluation |last3=UNICEF |author-link3=UNICEF |date=2024 |publisher=Health Effects Institute |pages=27 |issn=2578-6873}}</ref> In particular, [[Particulate pollution|fine particle pollution]] (PM<sub>2.5</sub>), which comes mostly from the burning of [[Fossil fuel|fossil fuels]], is a key risk factor for CAD.<ref>{{Cite journal |last1=Montone |first1=Rocco A. |last2=Rinaldi |first2=Riccardo |last3=Bonanni |first3=Alice |last4=Severino |first4=Anna |last5=Pedicino |first5=Daniela |last6=Crea |first6=Filippo |last7=Liuzzo |first7=Giovanna |date=2023-02-01 |title=Impact of air pollution on ischemic heart disease: Evidence, mechanisms, clinical perspectives |journal=Atherosclerosis |language=English |volume=366 |pages=22β31 |doi=10.1016/j.atherosclerosis.2023.01.013 |issn=0021-9150 |pmid=36696748|doi-access=free }}</ref>
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