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===Medications=== Many medications have constipation as a side effect. Some include (but are not limited to) [[opioid]]s, [[diuretics]], [[antidepressant]]s, [[antihistamine]]s, [[antispasmodic]]s, [[anticonvulsant]]s, [[tricyclic antidepressant]]s, [[antiarrythmics]], [[Beta blocker|beta-adrenoceptor antagonists]], [[anti-diarrheal]]s, 5-HT3 receptor antagonists such as [[ondansetron]], and aluminum [[antacid]]s.<ref name=walia/><ref name="ap01">{{Cite journal|date=August 2010|title=Managing constipation in adults|journal=Australian Prescriber|volume=33|issue=4|pages=116β9|author=Selby, Warwick|author2=Corte, Crispin|doi=10.18773/austprescr.2010.058|doi-access=free}}</ref> Certain [[calcium channel blocker]]s such as [[nifedipine]] and [[verapamil]] can cause severe constipation due to dysfunction of motility in the [[rectosigmoid colon]].<ref>{{cite journal|vauthors=Gallegos-Orozco JF, Foxx-Orenstein AE, Sterler SM, Stoa JM |title=Chronic constipation in the elderly|journal=The American Journal of Gastroenterology|volume=107|issue=1|pages=18β25|date=January 2012|pmid=21989145|doi=10.1038/ajg.2011.349|s2cid=205099253|type=Review}}</ref> Supplements such as calcium and iron supplements can also have constipation as a notable side effect.<ref>{{cite journal|first1=Kelvin|last1=Li|first2=Xia-Fang|last2=Wang|first3=Ding-You|last3=Li|first4=Yuan-Cheng|last4=Chen|title=The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health|journal=Clinical Interventions in Aging|date=28 November 2018|issn=1176-9092|pages=2443β2452|volume=13|pmid=30568435|pmc=6276611|doi=10.2147/CIA.S157523|first5=Lan-Juan|last5=Zhao|first6=Xiao-Gang|last6=Liu|first7=Yan-Fang|last7=Guo|first8=Jie|last8=Shen|first9=Xu|last9=Lin|first10=Jeffrey|last10=Deng|first11=Rou|last11=Zhou|first12=Hong-Wen|last12=Deng|doi-access=free }}</ref><ref name="q220">{{cite journal | last1=Parvataneni | first1=Swetha | last2=Maw | first2=Min | title=Ileus Due to Iron Pills: A Case Report and Literature Report on the Importance of Stool Softeners | journal=Cureus | publisher=Cureus Inc. | volume=12 | issue=6 | date=2024-03-14 | pages=e8392 | pmid=32637274 | doi=10.7759/cureus.8392 | doi-access=free | pmc=7331903 }}</ref>
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