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===Common genetic code=== {{further|Genetic code}} {| class="wikitable floatright" style="border: none; text-align: center;" | '''[[Amino acid]]s''' | style="background-color:#ffe75f; width: 50px;" | nonpolar | style="background-color:#b3dec0; width: 50px;" | polar | style="background-color:#bbbfe0; width: 50px;" | basic | style="background-color:#f8b7d3; width: 50px;" | acidic | style="border: none; width: 75px;" | | style="background-color:#B0B0B0;" | Stop codon |} {| class="wikitable floatright" |+ Standard genetic code !rowspan=2| 1st<br />base !colspan=8| 2nd base |- !colspan=2| {{{T|T}}} !colspan=2| C !colspan=2| A !colspan=2| G |- !rowspan=4| {{{T|T}}} | {{{T|T}}}{{{T|T}}}{{{T|T}}} |rowspan=2 style="background-color:#ffe75f" | [[Phenylalanine|Phenyl-<br>alanine]] | {{{T|T}}}C{{{T|T}}} |rowspan=4 style="background-color:#b3dec0" | [[Serine]] | {{{T|T}}}A{{{T|T}}} |rowspan=2 style="background-color:#b3dec0" | [[Tyrosine]] | {{{T|T}}}G{{{T|T}}} |rowspan=2 style="background-color:#b3dec0" | [[Cysteine]] |- | {{{T|T}}}{{{T|T}}}C | {{{T|T}}}CC | {{{T|T}}}AC | {{{T|T}}}GC |- | {{{T|T}}}{{{T|T}}}A |rowspan=6 style="background-color:#ffe75f" | [[Leucine]] | {{{T|T}}}CA | {{{T|T}}}AA | style="background-color:#B0B0B0;" | [[Stop codon|Stop]] <!--(''Ochre'')--> | {{{T|T}}}GA | style="background-color:#B0B0B0;" | [[Stop codon|Stop]] <!--(''Opal'')--> |- | {{{T|T}}}{{{T|T}}}G | {{{T|T}}}CG | {{{T|T}}}AG | style="background-color:#B0B0B0;" | [[Stop codon|Stop]] <!--(''Amber'')--> | {{{T|T}}}GG | style="background-color:#ffe75f;" | [[Tryptophan]] <!-- to make the columns roughly the same width --> |- ! rowspan="4" | C | C{{{T|T}}}{{{T|T}}} | CC{{{T|T}}} |rowspan=4 style="background-color:#ffe75f" | [[Proline]] | CA{{{T|T}}} |rowspan=2 style="background-color:#bbbfe0" | [[Histidine]] |CG{{{T|T}}} |rowspan=4 style="background-color:#bbbfe0" | [[Arginine]] |- |C{{{T|T}}}C |CCC |CAC |CGC |- |C{{{T|T}}}A |CCA |CAA |rowspan=2 style="background-color:#b3dec0" | [[Glutamine]] |CGA |- |C{{{T|T}}}G |CCG |CAG |CGG |- ! rowspan="4" | A |A{{{T|T}}}{{{T|T}}} |rowspan=3 style="background-color:#ffe75f" | [[Isoleucine]] |AC{{{T|T}}} |rowspan=4 style="background-color:#b3dec0" | [[Threonine]] <!-- to make the columns roughly the same width --> |AA{{{T|T}}} |rowspan=2 style="background-color:#b3dec0" | [[Asparagine]] |AG{{{T|T}}} |rowspan=2 style="background-color:#b3dec0" | [[Serine]] |- |A{{{T|T}}}C |ACC |AAC |AGC |- |A{{{T|T}}}A |ACA |AAA |rowspan=2 style="background-color:#bbbfe0" | [[Lysine]] |AGA |rowspan=2 style="background-color:#bbbfe0" | [[Arginine]] |- |A{{{T|T}}}G | style="background-color:#ffe75f;" | [[Methionine]] |ACG |AAG |AGG |- ! rowspan="4" | G |G{{{T|T}}}{{{T|T}}} |rowspan=4 style="background-color:#ffe75f" | [[Valine]] |GC{{{T|T}}} |rowspan=4 style="background-color:#ffe75f" | [[Alanine]] |GA{{{T|T}}} |rowspan=2 style="background-color:#f8b7d3" | [[Aspartic acid|Aspartic<br>acid]] |GG{{{T|T}}} |rowspan=4 style="background-color:#ffe75f" | [[Glycine]] |- |G{{{T|T}}}C |GCC |GAC |GGC |- |G{{{T|T}}}A |GCA |GAA |rowspan=2 style="background-color:#f8b7d3" | [[Glutamic acid|Glutamic<br>acid]] |GGA |- |G{{{T|T}}}G |GCG |GAG |GGG |- |} The [[genetic code]] (the "translation table" according to which DNA information is translated into [[amino acid]]s, and hence proteins) is nearly identical for all known lifeforms, from [[bacteria]] and [[archaea]] to [[animal]]s and [[plant]]s. The universality of this code is generally regarded by biologists as definitive evidence in favor of universal common descent.<ref name=Knight/> The way that [[Genetic code|codon]]s (DNA triplets) are mapped to [[amino acid]]s seems to be strongly optimised. Richard Egel argues that in particular the [[hydrophobic]] (non-polar) side-chains are well organised, suggesting that these enabled the earliest organisms to create [[peptide]]s with water-repelling regions able to support the essential electron exchange ([[redox]]) reactions for energy transfer.<ref name=Egel>{{cite journal |last1=Egel |first1=Richard |title=Primal Eukaryogenesis: On the Communal Nature of Precellular States, Ancestral to Modern Life |journal=Life |date=March 2012 |volume=2 |issue=1 |pages=170β212 |doi=10.3390/life2010170 |pmc=4187143 |pmid=25382122|bibcode=2012Life....2..170E |doi-access=free }}</ref>
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