Editing Coenzyme Q10 (section)

===Assessment===
Although CoQ<sub>10</sub> may be measured in [[blood plasma]], these measurements reflect dietary intake rather than tissue status. Currently, most clinical centers measure CoQ<sub>10</sub> levels in cultured skin [[fibroblast]]s, muscle [[biopsy|biopsies]], and blood mononuclear cells.<ref name="pmid21844807">{{cite journal | vauthors = Trevisson E, DiMauro S, Navas P, Salviati L | title = Coenzyme Q deficiency in muscle | journal = Current Opinion in Neurology | volume = 24 | issue = 5 | pages = 449–456 | date = October 2011 | pmid = 21844807 | doi = 10.1097/WCO.0b013e32834ab528 | hdl-access = free | hdl = 10261/129020 }}</ref> Culture fibroblasts can be used also to evaluate the rate of endogenous CoQ<sub>10</sub> biosynthesis, by measuring the uptake of [[carbon-14|<sup>14</sup>C]]-[[isotopic labeling|labeled]] [[p-Hydroxybenzoic acid|''p''-hydroxybenzoate]].<ref name="pmid18387363">{{cite journal | vauthors = Montero R, Sánchez-Alcázar JA, Briones P, Hernández AR, Cordero MD, Trevisson E, Salviati L, Pineda M, García-Cazorla A, Navas P, Artuch R | title = Analysis of coenzyme Q10 in muscle and fibroblasts for the diagnosis of CoQ<sub>10</sub> deficiency syndromes | journal = Clinical Biochemistry | volume = 41 | issue = 9 | pages = 697–700 | date = June 2008 | pmid = 18387363 | doi = 10.1016/j.clinbiochem.2008.03.007 | hdl-access = free | hdl = 11577/2447079 }}</ref>

CoQ<sub>10</sub> is studied as an adjunctive therapy to reduce inflammation in [[periodontitis]].<ref name="pmid37592831">{{cite journal |vauthors=Fawzy El-Sayed KM, Cosgarea R, Sculean A, Doerfer C |title=Can vitamins improve periodontal wound healing/regeneration? |journal=Periodontol 2000 |volume=94 |issue=1 |pages=539–602 |date=February 2024 |pmid=37592831 |doi=10.1111/prd.12513 |url=|doi-access=free }}</ref>