Editing Coeliac disease (section)

===Miscellaneous===
Coeliac disease has been linked with many conditions. In many cases, it is unclear whether the gluten-induced bowel disease is a causative factor or whether these conditions share a common predisposition.
* [[IgA deficiency]] is present in 2.3% of people with coeliac disease, and is itself associated with a tenfold increased risk of coeliac disease. Other features of this condition are an increased risk of infections and [[autoimmune disease]].<ref>{{cite journal |vauthors=Cunningham-Rundles C |title=Physiology of IgA and IgA deficiency |journal=J. Clin. Immunol. |volume=21 |issue=5 |pages=303–9 |date=September 2001 |pmid=11720003 |doi=10.1023/A:1012241117984}}</ref>
* [[Dermatitis herpetiformis]], an itchy cutaneous condition that has been linked to a transglutaminase enzyme in the skin, features small-bowel changes identical to those in coeliac disease and may respond to gluten withdrawal even if no gastrointestinal symptoms are present.<ref name=Marks>{{cite journal |vauthors=Marks J, Shuster S, Watson AJ |title=Small-bowel changes in dermatitis herpetiformis |journal=Lancet |volume=2 |issue=7476 |pages=1280–2 |year=1966 |pmid=4163419 |doi=10.1016/S0140-6736(66)91692-8}}</ref><ref>{{cite journal |vauthors=Nicolas ME, Krause PK, Gibson LE, Murray JA |title=Dermatitis herpetiformis |journal=Int. J. Dermatol. |volume=42 |issue=8 |pages=588–600 |date=August 2003 |pmid=12890100 |doi=10.1046/j.1365-4362.2003.01804.x }}</ref>
* [[Growth failure]] and/or [[delayed puberty|pubertal delay]] in later childhood can occur even without obvious bowel symptoms or severe [[malnutrition]]. Evaluation of growth failure often includes coeliac screening.<ref name=Lancet2009/>
* [[Pregnancy complication]]s can occur if coeliac disease is [[pre-existing disease in pregnancy|pre-existing]] or later acquired, with significant outcomes including [[miscarriage]], [[intrauterine growth restriction]], [[low birthweight]] and [[preterm birth]].<ref name="TersigniCastellani2014">{{cite journal |vauthors=Tersigni C, Castellani R, de Waure C, Fattorossi A, De Spirito M, Gasbarrini A, Scambia G, Di Simone N |title=Celiac disease and reproductive disorders: meta-analysis of epidemiologic associations and potential pathogenic mechanisms |journal=Human Reproduction Update |volume=20 |issue=4 |pages=582–93 |year=2014 |pmid=24619876 |doi=10.1093/humupd/dmu007 |doi-access=free|hdl=10807/56796 |hdl-access=free }}</ref>
* [[Hyposplenism]] (a small and underactive [[spleen]])<ref name=Ferguson>{{cite journal |vauthors=Ferguson A, Hutton MM, Maxwell JD, Murray D |title=Adult coeliac disease in hyposplenic patients |journal=Lancet |volume=1 |issue=7639 |pages=163–4 |year=1970 |pmid=4189238 |doi=10.1016/S0140-6736(70)90405-8}}</ref> occurs in about a third of cases and may predispose to infection given the role of the spleen in protecting against harmful bacteria.<ref name=Lancet2009/>
* Abnormal [[liver function test]]s (randomly detected on blood tests) may be seen.<ref name=Lancet2009/>
* [[Depression (mood)|Depression]], [[anxiety]] and other mental health disorders<ref>{{cite journal | vauthors = Zingone F, Swift GL, Card TR, Sanders DS, Ludvigsson JF, Bai JC | title = Psychological morbidity of celiac disease: A review of the literature | journal = United European Gastroenterology Journal | volume = 3 | issue = 2 | pages = 136–145 | date = April 2015 | pmid = 25922673 | pmc = 4406898 | doi = 10.1177/2050640614560786 }}</ref>

Coeliac disease is associated with several other medical conditions, many of which are autoimmune disorders: [[diabetes mellitus type 1]], [[hypothyroidism]], [[primary biliary cholangitis]], [[microscopic colitis]], [[ataxia|gluten ataxia]], [[psoriasis]], [[vitiligo]], [[autoimmune hepatitis]], [[primary sclerosing cholangitis]], and more.<ref name=Lund2015 />