Jump to content
Main menu
Main menu
move to sidebar
hide
Navigation
Main page
Recent changes
Random page
Help about MediaWiki
Special pages
Niidae Wiki
Search
Search
Appearance
Create account
Log in
Personal tools
Create account
Log in
Pages for logged out editors
learn more
Contributions
Talk
Editing
Centrifuge
(section)
Page
Discussion
English
Read
Edit
View history
Tools
Tools
move to sidebar
hide
Actions
Read
Edit
View history
General
What links here
Related changes
Page information
Appearance
move to sidebar
hide
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
=== Laboratory separations === {{main|Laboratory centrifuge}} [[File:FDA Mobile Lab 4008 (4460533736).jpg|thumb|Samples placed in a small laboratory centrifuge]] A wide variety of laboratory-scale centrifuges are used in chemistry, biology, biochemistry and [[clinical medicine]] for isolating and separating suspensions and immiscible liquids. They vary widely in speed, capacity, temperature control, and other characteristics. Laboratory centrifuges often can accept a range of different fixed-angle and swinging bucket rotors able to carry different numbers of centrifuge tubes and rated for specific maximum speeds. Controls vary from simple electrical timers to programmable models able to control acceleration and deceleration rates, running speeds, and temperature regimes. Ultracentrifuges spin the rotors under vacuum, eliminating air resistance and enabling exact temperature control. [[Zonal rotor]]s and [[continuous flow]] systems are capable of handing bulk and larger sample volumes, respectively, in a laboratory-scale instrument.<ref name=":0" /> [[File:Blood Research- Saving Lives (8384) (9759061442).jpg|thumb|Whole blood is often separated, using a centrifuge, into components for storage and transport]] An application in laboratories is blood separation. Blood separates into cells and proteins (RBC, WBC, platelets, etc.) and serum. [[DNA]] preparation is another common application for pharmacogenetics and clinical diagnosis. DNA samples are purified and the DNA is prepped for separation by adding buffers and then centrifuging it for a certain amount of time. The blood waste is then removed and another buffer is added and spun inside the centrifuge again. Once the blood waste is removed and another buffer is added the pellet can be suspended and cooled. Proteins can then be removed and the entire thing can be centrifuged again and the DNA can be isolated completely. Specialized [[cytocentrifuge]]s are used in medical and biological laboratories to concentrate cells for microscopic examination.<ref>{{cite journal |last1=Stokes |first1=Barry O. |year=2004 |title=Principles of Cytocentrifugation |journal=Laboratory Medicine |volume=35 |issue=7 |pages=434β437 |issn=0007-5027 |doi=10.1309/FTT59GWKDWH69FB0 |doi-access=free}}</ref>
Summary:
Please note that all contributions to Niidae Wiki may be edited, altered, or removed by other contributors. If you do not want your writing to be edited mercilessly, then do not submit it here.
You are also promising us that you wrote this yourself, or copied it from a public domain or similar free resource (see
Encyclopedia:Copyrights
for details).
Do not submit copyrighted work without permission!
Cancel
Editing help
(opens in new window)
Search
Search
Editing
Centrifuge
(section)
Add topic