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===Lasting signs=== A dog that survives distemper can have complications afterwards. The most prevalent complication is hard pad disease, in which the skin on paw pads and skin on end of the nose thicken. Another lasting symptom that is common is [[enamel hypoplasia]]. Puppies can have damage to the enamel of teeth that are not completely formed or have not yet grown through the gums. This results from the virus killing the cells responsible for manufacturing the tooth enamel. These affected teeth tend to erode quickly.<ref name=Insider2012>{{cite web | title = Canine Distemper: What You Need To Know | work = Veterinary Insider | url = http://www.veterinaryinsider.com/public/Canine-Distemper-What-You-Need-To-Know.cfm | access-date = 2012-04-09 | url-status = dead | archive-url = https://web.archive.org/web/20120502040331/http://www.veterinaryinsider.com/public/Canine-Distemper-What-You-Need-To-Know.cfm | archive-date = 2012-05-02 | date = 2010-12-06 }}</ref>[[File:Arctic-Lineage-Canine-Distemper-Virus-as-a-Cause-of-Death-in-Apennine-Wolves-(Canis-lupus)-in-Italy-pone.0082356.s001.ogv|thumb|[[Italian wolf]] in advanced stage of infection.]] Life-threatening complications can include nervous-system degeneration. Dogs that have been infected with distemper can have a progressive deterioration of mental abilities and motor skills. With time, the dog can develop seizures, paralysis, a reduction in sight, and incoordination. These dogs are usually humanely euthanized because of the immense pain and suffering they face.<ref name=Insider2012 />
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