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====Zona fasciculata==== The [[zona fasciculata]] is situated between the zona glomerulosa and zona reticularis. Cells in this layer are responsible for producing [[glucocorticoid]]s such as [[cortisol]].<ref name=Kaplan.Physio>{{cite book|title=Kaplan USMLE Step 1 Physiology Lecture Notes|year=2011|author=Dunn R. B.|author2=Kudrath W.|author3=Passo S.S.|author4=Wilson L.B.|pages=263β289|chapter=10}}</ref> It is the largest of the three layers, accounting for nearly 80% of the volume of the cortex.<ref name="ross">{{cite book | title=Histology: A Text and Atlas | url=https://archive.org/details/histologytextatl00ross | url-access=limited | publisher=Lippincott Williams & Wilkins |vauthors=Ross M, Pawlina W | year=2011 | isbn=978-0-7817-7200-6 | pages=[https://archive.org/details/histologytextatl00ross/page/n727 708], 780| edition=6th}}</ref> In the zona fasciculata, cells are arranged in columns radially oriented towards the medulla. Cells contain numerous lipid droplets, abundant [[Mitochondrion|mitochondria]] and a complex [[endoplasmic reticulum#smooth endoplasmic reticulum|smooth endoplasmic reticulum]].<ref name="wheater" />
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