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===Microbiome alterations=== [[Fecal microbiota transplant]]ation<ref>{{cite news | vauthors = Haridy R |title=Gut bacteria from young mice reverse signs of brain aging in old mice |url=https://newatlas.com/science/microbiome-brain-aging-gut-bacteria-neuroscience/ |access-date=21 September 2021 |work=New Atlas |date=10 August 2021}}</ref><ref>{{cite journal | vauthors = Boehme M, Guzzetta KE, Bastiaanssen TF, Van De Wouw M, Moloney GM, Gual-Grau A, Spichak S, Olavarría-Ramírez L, Fitzgerald P, Morillas E, Ritz NL, Jaggar M, Cowan CS, Crispie F, Donoso F, Halitzki E, Neto MC, Sichetti M, Golubeva AV, Fitzgerald RS, Claesson MJ, Cotter PD, O'Leary OF, Dinan TG, Cryan JF | display-authors = 6 |title=Microbiota from young mice counteracts selective age-associated behavioral deficits |journal=Nature Aging |date=August 2021 |volume=1 |issue=8 |pages=666–676 |doi=10.1038/s43587-021-00093-9 | pmid = 37117767 |language=en |issn=2662-8465|doi-access=free }}</ref> and [[probiotics]] are being investigated as means for life and healthspan extension.<ref>{{cite journal | vauthors = Sharma D, Kober MM, Bowe WP | title = Anti-Aging Effects of Probiotics | journal = Journal of Drugs in Dermatology | volume = 15 | issue = 1 | pages = 9–12 | date = January 2016 | pmid = 26741377 | url = https://pubmed.ncbi.nlm.nih.gov/26741377/ }}</ref><ref>{{cite journal | vauthors = Ayala FR, Bauman C, Cogliati S, Leñini C, Bartolini M, Grau R | title = Microbial flora, probiotics, ''Bacillus subtilis'' and the search for a long and healthy human longevity | journal = Microbial Cell | volume = 4 | issue = 4 | pages = 133–136 | date = March 2017 | pmid = 28435840 | pmc = 5376353 | doi = 10.15698/mic2017.04.569 }}</ref><ref>{{cite journal | vauthors = Tsai YC, Cheng LH, Liu YW, Jeng OJ, Lee YK | title = Gerobiotics: probiotics targeting fundamental aging processes | journal = Bioscience of Microbiota, Food and Health | volume = 40 | issue = 1 | pages = 1–11 | date = 2021 | pmid = 33520563 | pmc = 7817508 | doi = 10.12938/bmfh.2020-026 }}</ref>
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