Editing Zebrafish (section)

===Cardiovascular disease===
In cardiovascular research, the zebrafish has been used to model human myocardial infarction model. The zebrafish heart completely regenerates after about 2 months of injury without any scar formation.<ref>{{cite journal |doi=10.1186/1471-213X-11-21 |pmid=21473762 |pmc=3078894 |title=The zebrafish heart regenerates after cryoinjury-induced myocardial infarction |year=2011 |last1=Chablais |first1=Fabian |last2=Veit |first2=Julia |last3=Rainer |first3=Gregor |last4=Jaźwińska |first4=Anna |journal=[[BMC Developmental Biology]] |volume=11 |page=21 |doi-access=free}}</ref> The [[Alpha-1 adrenergic receptor|Alpha-1 adrenergic signalling]] mechanism involved in this process was identified in a 2023 study.<ref>{{Cite journal |last1=Apaydin |first1=Onur |last2=Altaikyzy |first2=Akerke |last3=Filosa |first3=Alessandro |last4=Sawamiphak |first4=Suphansa |date=2023-11-20 |title=Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages |journal=[[Developmental Cell]] |volume=58 |issue=22 |pages=2460–2476.e7 |doi=10.1016/j.devcel.2023.09.011 |pmid=37875117 |s2cid=264449103 |issn=1534-5807 |doi-access=free}}</ref> Zebrafish is also used as a model for [[Coagulation|blood clotting]], [[Angiogenesis|blood vessel development]], and [[congenital heart defect|congenital heart and kidney disease]].<ref>{{cite journal |vauthors=Drummond IA |title=Kidney development and disease in the zebrafish |journal=[[Journal of the American Society of Nephrology]] |volume=16 |issue=2 |pages=299–304 |date=February 2005 |pmid=15647335 |doi=10.1681/ASN.2004090754 |s2cid=25428361 |doi-access=}}</ref>