Editing Quorum sensing (section)

===Inhibition===

[[Closantel]] and [[triclosan]] are known inhibitors of quorum sensing enzymes.<ref name=":32">{{cite journal | vauthors = Basavaraju M, Sisnity VS, Palaparthy R, Addanki PK | title = Quorum quenching: Signal jamming in dental plaque biofilms | journal = Journal of Dental Sciences | volume = 11 | issue = 4 | pages = 349–352 | date = December 2016 | pmid = 30894996 | pmc = 6395279 | doi = 10.1016/j.jds.2016.02.002 }}</ref> Closantel induces aggregation of the [[histidine kinase]] sensor in two-component signalling. The latter disrupts the synthesis of a class of signalling molecules known as [[N-Acyl homoserine lactone|''N''-acyl homoserine lactones]] (AHLs) by blocking the [[Enoyl-acyl carrier protein reductase|enoyl-acyl carrier protein (ACP) reductase]].<ref name=":32" /><ref>{{cite journal | vauthors = Zhang LH, Dong YH | title = Quorum sensing and signal interference: diverse implications | journal = Molecular Microbiology | volume = 53 | issue = 6 | pages = 1563–1571 | date = September 2004 | pmid = 15341639 | doi = 10.1111/j.1365-2958.2004.04234.x | s2cid = 39018931 | doi-access = free }}</ref>