Editing Glucose (section)

===Chromatographic methods===
In particular, for the analysis of complex mixtures containing glucose, e.g. in honey, chromatographic methods such as [[high performance liquid chromatography]] and [[gas chromatography]]<ref name="Galant" /> are often used in combination with [[mass spectrometry]].<ref>{{cite journal | last1 = Sanz | first1 = M. L. | last2 = Sanz | first2 = J. | last3 = Martínez-Castro | first3 = I. | year = 2004| title = Gas chromatographic-mass spectrometric method for the qualitative and quantitative determination of disaccharides and trisaccharides in honey. | journal = [[Journal of Chromatography A]] | volume = 1059 | issue = 1–2| pages = 143–148 | pmid = 15628134 | doi = 10.1016/j.chroma.2004.09.095 }}</ref><ref name="mpg-210190">{{cite web|title=Glucose mass spectrum|periodical=Golm Metabolome Database|url=http://gmd.mpimp-golm.mpg.de/Spectrums/8dee81a1-8d98-4a73-b55d-9de42f10e190.aspx|access-date=4 June 2018|last=[[Max Planck Institute of Molecular Plant Physiology]] in Golm Database|date=19 July 2007|archive-url=https://web.archive.org/web/20180909000409/http://gmd.mpimp-golm.mpg.de/Spectrums/8dee81a1-8d98-4a73-b55d-9de42f10e190.aspx|archive-date=9 September 2018|url-status=live}}</ref> Taking into account the isotope ratios, it is also possible to reliably detect honey adulteration by added sugars with these methods.<ref>{{cite journal | last1 = Cabañero | first1 = A. I. | last2 = Recio | first2 = J. L. | last3 = Rupérez | first3 = M. | year = 2006| title = Liquid chromatography coupled to isotope ratio mass spectrometry: a new perspective on honey adulteration detection. | journal = [[J Agric Food Chem]] | volume = 54 | issue = 26| pages = 9719–9727 | pmid = 17177492 | doi = 10.1021/jf062067x | bibcode = 2006JAFC...54.9719C }}</ref> Derivatization using silylation reagents is commonly used.<ref>{{Cite journal |pmid=24054643|year=2013|last1=Becker|first1=M.|title=Ethoximation-silylation approach for mono- and disaccharide analysis and characterization of their identification parameters by GC/MS|journal=Talanta|volume=115|pages=642–51|last2=Liebner|first2=F.|last3=Rosenau|first3=T.|last4=Potthast|first4=A.|doi=10.1016/j.talanta.2013.05.052}}</ref> Also, the proportions of di- and trisaccharides can be quantified.

====In vivo analysis====
Glucose uptake in cells of organisms is measured with [[2-deoxy-D-glucose]] or [[fluorodeoxyglucose]].<ref name="Dwyer">Donard Dwyer: ''Glucose Metabolism in the Brain''. Academic Press, 2002, {{ISBN|978-0-123-66852-3}}, p.&nbsp;XIII.</ref> (<sup>18</sup>F)fluorodeoxyglucose is used as a tracer in [[positron emission tomography]] in oncology and neurology,<ref name="gdch">[[Gesellschaft Deutscher Chemiker]]: [http://www.gdch.de/strukturen/fg/nuklear/posi2.pdf wayback=20100331071121 ''Anlagen zum Positionspapier der Fachgruppe Nuklearchemie''] {{Webarchive|url=https://web.archive.org/web/20100331071121/http://www.gdch.de/strukturen/fg/nuklear/posi2.pdf |date=31 March 2010 }}, February 2000.</ref> where it is by far the most commonly used diagnostic agent.<ref>{{Cite journal |doi=10.1155/2014/214748 |pmc=4058687 |pmid=24991541|year=2014 |last1=Maschauer |first1=S. |title=Sweetening pharmaceutical radiochemistry by (18)f-fluoroglycosylation: A short review |journal=BioMed Research International |volume=2014 |pages=1–16 |last2=Prante |first2=O. |doi-access=free }}</ref>