Editing Infant formula (section)

==== Probiotics ====
Randomized, controlled trials completed in the 2000s have shown limited and short term clinical benefits for the use of [[probiotics]] in infants' diet.<ref name="probiotics">Carvalho, R.S., Michail, S., Ashai-Khan, F., Mezoff, A.G. (2008). An Update on Pediatric Gastroenterology and Nutrition: A Review of Some Recent Advances. ''Curr Probl Pediatr Adolesc Health Care,'' 204–228.</ref> A 2018 clinical study using the multistrain [[De Simone Formulation]] probiotic showed it helped some infants reduce symptoms of infant colic.<ref>{{cite journal | pmc=5852771 | year=2018 | last1=Baldassarre | first1=M. E. | last2=Di Mauro | first2=A. | last3=Tafuri | first3=S. | last4=Rizzo | first4=V. | last5=Gallone | first5=M. S. | last6=Mastromarino | first6=P. | last7=Capobianco | first7=D. | last8=Laghi | first8=L. | last9=Zhu | first9=C. | last10=Capozza | first10=M. | last11=Laforgia | first11=N. | title=Effectiveness and Safety of a Probiotic-Mixture for the Treatment of Infantile Colic: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial with Fecal Real-Time PCR and NMR-Based Metabolomics Analysis | journal=Nutrients | volume=10 | issue=2 | page=195 | doi=10.3390/nu10020195 | pmid=29439395 | doi-access=free }}</ref>  The safety of probiotics in general and in infants, especially preterm infants, has been investigated in a limited number of controlled trials. The findings thus far suggest probiotics are generally safe, though the research is preliminary and has yet to provide definitive conclusions.<ref name="probiotics"/>