Editing Hypoglycemia (section)

==History==
Hypoglycemia was first discovered by [[James Collip]] when he was working with [[Frederick Banting]] on purifying insulin in 1922.<ref name=":1" /> Collip was asked to develop an assay to measure the activity of insulin.<ref name=":1" /> He first injected insulin into a rabbit, and then measured the reduction in blood-glucose levels.<ref name=":1" /> Measuring blood glucose was a time-consuming step.<ref name=":1" /> Collip observed that if he injected rabbits with a too large a dose of insulin, the rabbits began convulsing, went into a coma, and then died.<ref name=":1" /> This observation simplified his assay.<ref name=":1" /> He defined one unit of insulin as the amount necessary to induce this convulsing hypoglycemic reaction in a rabbit.<ref name=":1" /> Collip later found he could save money, and rabbits, by injecting them with glucose once they were convulsing.<ref name=":1">{{Cite web |title=Collip discovers hypoglycemia |url=https://tacomed.com/chapter-7-standardization/collip-discovers-hypoglycemia/ |url-status=dead |archive-url=https://web.archive.org/web/20170908182717/https://tacomed.com/chapter-7-standardization/collip-discovers-hypoglycemia/ |archive-date=8 September 2017 |access-date=18 June 2017 |website=Treating Diabetes}}</ref>