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===Colorectal cancer=== The risk of [[colorectal cancer]] is significantly increased in people with ulcerative colitis after ten years if involvement is beyond the [[splenic flexure]]. People with backwash ileitis might have an increased risk for colorectal carcinoma.<ref>{{cite journal | vauthors = Patil DT, Odze RD | title = Backwash Is Hogwash: The Clinical Significance of Ileitis in Ulcerative Colitis | journal = The American Journal of Gastroenterology | volume = 112 | issue = 8 | pages = 1211β1214 | date = August 2017 | pmid = 28631729 | doi = 10.1038/ajg.2017.182 | s2cid = 10801391 }}</ref> Those people with only proctitis usually have no increased risk.<ref name=ACG_Guidelines_2019 /> It is recommended that people have screening [[colonoscopies]] with random biopsies to look for [[dysplasia]] after eight years of disease activity, at one to two year intervals.<ref>{{cite journal | vauthors = Leighton JA, Shen B, Baron TH, Adler DG, Davila R, Egan JV, Faigel DO, Gan SI, Hirota WK, Lichtenstein D, Qureshi WA, Rajan E, Zuckerman MJ, VanGuilder T, Fanelli RD | title = ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease | journal = Gastrointestinal Endoscopy | volume = 63 | issue = 4 | pages = 558β565 | date = April 2006 | pmid = 16564852 | doi = 10.1016/j.gie.2006.02.005 }}</ref>
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