Editing Gainesville, Florida (section)

===Major roads===
[[File:Dsg Gainesville 13th and University Intersection Approach 20050507.jpg|thumb|Heading east on University Avenue, approaching 13th Street ([[U.S. Route 441 in Florida|US 441]]) intersection]]

Gainesville has an extensive road system, which is served by [[Interstate 75 in Florida|Interstate 75]], and several [[State Roads in Florida|Florida State Routes]], including State routes [[State Road 20 (Florida)|20]], [[State Road 24 (Florida)|24]], and [[State Road 26 (Florida)|26]]. Gainesville is also served by [[U.S. Route 441 in Florida|US 441]] and nearby [[U.S. Route 301 in Florida|US 301]], which give a direct route to [[Jacksonville, Florida|Jacksonville]], [[Ocala, Florida|Ocala]], and [[Orlando, Florida|Orlando]].
{{See also|List of county roads in Alachua County, Florida}}
* {{jct|I|75|state=FL}} runs northwest and southeast across the western edge of the city, with interchanges at SR 121/SR 331 (exit 382), SR 24 (exit 384), SR 26 (exit 387), and [[Florida State Road 222|SR 222]] (Exit 390).
* {{jct|US|441|state=FL}} is the main local north–south road through Gainesville. It runs on the eastern edge of the University of Florida. It is known to locals as 13th Street, before curving to the northwest and finally joining SR 20, converting into an additional hidden state road. At the intersection of [[Florida State Road 121|SR 121]], the ''DeSoto Trail'' moves from SR 121 to US 441.
* {{jct|SR|20|state=FL}} runs northwest and southeast through Gainesville. In east Gainesville, the road again becomes a stand-alone four-lane highway as it heads to [[Hawthorne, Florida|Hawthorne]], [[Interlachen, Florida|Interlachen]], and [[Palatka, Florida|Palatka]]. Northwest of Gainesville, SR 20 coincides with US 441 as a hidden state road through the town of [[Alachua, Florida|Alachua]] before splitting at the fork a half-mile from downtown [[High Springs, Florida|High Springs]]. SR 20 then coincides with [[U.S. Route 27 in Florida|US 27]] as it heads to [[Fort White, Florida|Fort White]], [[Branford, Florida|Branford]], [[Mayo, Florida|Mayo]], [[Perry, Florida|Perry]], and [[Tallahassee, Florida|Tallahassee]].
* {{jct|SR|24|state=FL}} runs northeast and southwest through Gainesville. The northeast corner of SR 24 and [[State Road 222 (Florida)|SR 222]] is the site of the [[Gainesville Regional Airport]], before heading to [[Waldo, Florida|Waldo]], [[Starke, Florida|Starke]], and [[Jacksonville, Florida|Jacksonville]] (Via.[[U.S. Route 301 in Florida|U.S. Route 301]])(Gainesville-Jacksonville Highway). Southwest of Gainesville, SR 24 passes through the towns of [[Archer, Florida|Archer]] and [[Bronson, Florida|Bronson]] before ending at [[Cedar Key, Florida|Cedar Key]].
* {{jct|SR|26|state=FL}} is the main local east–west road through Gainesville. West of the city, it spans from [[Fanning Springs, Florida|Fanning Springs]] to [[Trenton, Florida|Trenton]], [[Newberry, Florida|Newberry]], and [[Jonesville, Florida|Jonesville]]. Eastward, SR 26 heads to [[Melrose, Florida|Melrose]] before reaching its terminus at [[Putnam Hall, Florida|Putnam Hall]] in Putnam County.
* {{jct|SR|120|state=FL}} runs east and west through the city. Its western end is at the junction with US 441, its eastern end at the junction with SR 24.
* {{jct|SR|121|state=FL}} runs north and south on the western part of the city. The DeSoto Trail breaks away as SR 121 heads north to [[Lake Butler, Union County, Florida|Lake Butler]], [[Raiford, Florida|Raiford]], and [[Macclenny, Florida|Macclenny]]. Southward, it travels to [[Williston, Florida|Williston]] before reaching its terminus at Lebanon Station.
* {{jct|SR|222|state=FL}} runs east and west on the northern part of the city. Its western end of state maintenance is at the junction with I-75 before continuing as County Road 222 to County Road 241, while its eastern end is at the junction with SR 26 a few miles east of the [[Gainesville Regional Airport]].
* {{jct|SR|331|state=FL}} runs northeast and southwest through the city. It also serves as a truck route for State Roads 24, 26, and 121. Despite skirting the Gainesville City Limits, SR&nbsp;331 runs north and south as a four-lane divided rural highway.

The city's streets lie on a grid system, with four quadrants (NW, NE, SW and SE). All streets are numbered, except for a few major thoroughfares, many of which are named for the towns they lead to (such as [[Waldo, Florida|Waldo]] Road (SR 24), [[Hawthorne, Florida|Hawthorne]] Road (SR 20), [[Williston, Florida|Williston]] Road (SR 121/SR 331), [[Archer, Florida|Archer]] Road (also SR 24) and [[Newberry, Florida|Newberry]] Road (SR 26)). Streets called Avenues, Places, Roads or Lanes (often remembered by use of the acronym "APRiL") generally run east–west, while other streets (including Streets, Drives, Terraces, and Ways) generally run north–south.