Editing Epigenetics (section)

====Aging====
{{See also|DNA methylation#In aging|Hallmarks of aging#Epigenomic alterations}}
Epigenetics play a major role in [[brain aging]] and age-related cognitive decline, with relevance to [[life extension]].<ref>{{cite journal | vauthors = Barter JD, Foster TC | title = Aging in the Brain: New Roles of Epigenetics in Cognitive Decline | journal = The Neuroscientist | volume = 24 | issue = 5 | pages = 516–525 | date = October 2018 | pmid = 29877135 | doi = 10.1177/1073858418780971 | s2cid = 46965080 }}</ref><ref>{{cite journal | vauthors = Harman MF, Martín MG | title = Epigenetic mechanisms related to cognitive decline during aging | journal = Journal of Neuroscience Research | volume = 98 | issue = 2 | pages = 234–246 | date = February 2020 | pmid = 31045277 | doi = 10.1002/jnr.24436 | s2cid = 143423862 }}</ref><ref>{{cite journal | vauthors = Braga DL, Mousovich-Neto F, Tonon-da-Silva G, Salgueiro WG, Mori MA | title = Epigenetic changes during ageing and their underlying mechanisms | journal = Biogerontology | volume = 21 | issue = 4 | pages = 423–443 | date = August 2020 | pmid = 32356238 | doi = 10.1007/s10522-020-09874-y | s2cid = 254292058 }}</ref><ref>{{cite journal | vauthors = Zhang W, Qu J, Liu GH, Belmonte JC | title = The ageing epigenome and its rejuvenation | journal = Nature Reviews. Molecular Cell Biology | volume = 21 | issue = 3 | pages = 137–150 | date = March 2020 | pmid = 32020082 | doi = 10.1038/s41580-019-0204-5 | s2cid = 211028527 }}</ref><ref>{{cite journal | vauthors = Simpson DJ, Olova NN, Chandra T | title = Cellular reprogramming and epigenetic rejuvenation | journal = Clinical Epigenetics | volume = 13 | issue = 1 | pages = 170 | date = September 2021 | pmid = 34488874 | pmc = 8419998 | doi = 10.1186/s13148-021-01158-7 | doi-access = free }}</ref>