Editing Aspirin (section)

===Central effects===
Large doses of [[salicylate]], a metabolite of aspirin, cause temporary [[tinnitus]] (ringing in the ears) based on experiments in rats, as the action on [[arachidonic acid]] and [[NMDA receptor]]s cascade.<ref name="Gutton">{{cite journal |vauthors = Guitton MJ, Caston J, Ruel J, Johnson RM, Pujol R, Puel JL |title = Salicylate induces tinnitus through activation of cochlear NMDA receptors |journal = The Journal of Neuroscience |volume = 23 |issue = 9 |pages = 3944–52 |date = May 2003 |pmid = 12736364 |pmc = 6742173 |doi = 10.1523/JNEUROSCI.23-09-03944.2003 }}</ref>