Editing Cystic fibrosis (section)

===Ecological therapy===
It has previously been shown that inter-species interactions are an important contributor to the pathology of CF lung infections. Examples include the production of antibiotic degrading enzymes such as β-lactamases and the production of metabolic by-products such as short-chain fatty acids (SCFAs) by anaerobic species, which can enhance the pathogenicity of traditional pathogens such as ''Pseudomonas aeruginosa''.<ref name="pmid26774156">{{cite journal | vauthors = Sherrard LJ, McGrath SJ, McIlreavey L, Hatch J, Wolfgang MC, Muhlebach MS, Gilpin DF, Elborn JS, Tunney MM | title = Production of extended-spectrum β-lactamases and the potential indirect pathogenic role of Prevotella isolates from the cystic fibrosis respiratory microbiota | journal = International Journal of Antimicrobial Agents | volume = 47 | issue = 2 | pages = 140–145 | date = February 2016 | pmid = 26774156 | pmc = 4746055 | doi = 10.1016/j.ijantimicag.2015.12.004 }}</ref> Due to this, it has been suggested that the direct alteration of CF microbial community composition and metabolic function would provide an alternative to traditional antibiotic therapies.<ref name="Khanolkar"/>