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===Retinal vein occlusion=== It is a widespread habit among eye specialists (ophthalmologists) to prescribe aspirin as an add-on medication for patients with retinal vein occlusion (RVO), such as [[central retinal vein occlusion]] (CRVO) and [[branch retinal vein occlusion]] (BRVO).{{medical citation needed|date=April 2025}} The reason of this widespread use is the evidence of its proven effectiveness in major systemic venous [[Thrombosis|thrombotic]] disorders, and it has been assumed that may be similarly beneficial in various types of retinal vein occlusion.{{medical citation needed|date=April 2025}} However, a large-scale investigation based on data of nearly 700 patients showed "that aspirin or other antiplatelet aggregating agents or anticoagulants adversely influence the visual outcome in patients with CRVO and hemi-CRVO, without any evidence of protective or beneficial effect".<ref name="pmid24769221">{{cite journal |vauthors = Hayreh SS |title = Ocular vascular occlusive disorders: natural history of visual outcome |journal = Progress in Retinal and Eye Research |volume = 41 |pages = 1β25 |date = July 2014 |pmid = 24769221 |pmc = 4073304 |doi = 10.1016/j.preteyeres.2014.04.001 }}</ref> Several expert groups, including the [[Royal College of Ophthalmologists]], recommended against the use of antithrombotic drugs (incl. aspirin) for patients with RVO.<ref name="pmid26780742">{{cite journal |vauthors = Ageno W, Beyer-Westendorf J, Garcia DA, Lazo-Langner A, McBane RD, Paciaroni M |title = Guidance for the management of venous thrombosis in unusual sites |journal = Journal of Thrombosis and Thrombolysis |volume = 41 |issue = 1 |pages = 129β43 |date = January 2016 |pmid = 26780742 |pmc = 4715841 |doi = 10.1007/s11239-015-1308-1 }}</ref>
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