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===Preventing and treating vitamin A deficiency=== {{Main|Vitamin A deficiency}} Recognition of its prevalence and consequences has led to governments and non-government organizations promoting vitamin A fortification of foods<ref name=FortifMap/> and creating programs that administer large bolus-size oral doses of vitamin A to young children every four to six months.<ref name="Wirth2017"/> In 2008, the [[World Health Organization]] estimated that vitamin A supplementation over a decade in 40 countries averted 1.25 million deaths due to vitamin A deficiency.<ref>{{cite web |url=https://www.who.int/nutrition/topics/vad/en/index.html |title=Micronutrient Deficiencies β Vitamin A |access-date=9 April 2008 |publisher=World Health Organization |archive-url=https://web.archive.org/web/20110127030721/https://www.who.int/nutrition/topics/vad/en/index.html |archive-date=27 January 2011 |url-status=dead}}</ref> A Cochrane review reported that vitamin A supplementation is associated with a clinically meaningful reduction in morbidity and mortality in children ages six month to five years of age. All-cause mortality was reduced by 14%, and incidence of [[diarrhea]] by 12%.<ref name="Imdad2017">{{cite journal | vauthors = Imdad A, Mayo-Wilson E, Haykal MR, Regan A, Sidhu J, Smith A, Bhutta ZA | title = Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age | journal = The Cochrane Database of Systematic Reviews | volume = 3 | issue = 11 | pages = CD008524 | date = March 2022 | pmid = 35294044 | pmc = 8925277 | doi = 10.1002/14651858.CD008524.pub4 }}</ref> However, a Cochrane review by the same group concluded there was insufficient evidence to recommend blanket vitamin A supplementation for infants one to six months of age, as it did not reduce infant mortality or morbidity.<ref name="Imdad2016"/>
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