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===Neuronal replacement=== [[Stem-cell therapy]] is used to replace damaged neurons by transplantation of [[stem cell]]s into affected regions of the brain. Experiments in animal models (rats and mice only) have yielded positive results.<ref name="Holley Kamdjou Reidling Fury pp. 329β342">{{cite journal | vauthors = Holley SM, Kamdjou T, Reidling JC, Fury B, Coleal-Bergum D, Bauer G, Thompson LM, Levine MS, Cepeda C | title = Therapeutic effects of stem cells in rodent models of Huntington's disease: Review and electrophysiological findings | journal = CNS Neuroscience & Therapeutics | volume = 24 | issue = 4 | pages = 329β342 | date = April 2018 | pmid = 29512295 | pmc = 6489814 | doi = 10.1111/cns.12839 | publisher = Wiley }}</ref> Whatever their future therapeutic potential, stem cells are already a valuable tool for studying Huntington's disease in the laboratory.<ref>{{cite journal | vauthors = Cundiff PE, Anderson SA | title = Impact of induced pluripotent stem cells on the study of central nervous system disease | journal = Current Opinion in Genetics & Development | volume = 21 | issue = 3 | pages = 354β61 | date = June 2011 | pmid = 21277194 | pmc = 3932563 | doi = 10.1016/j.gde.2011.01.008}}</ref>
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