Editing Ehlers–Danlos syndrome (section)

=== Differential diagnosis ===
Several disorders share some characteristics with EDS. For example, in [[cutis laxa]], the skin is loose, hanging, and wrinkled. In EDS, the skin can be pulled away from the body, but is elastic and returns to normal when let go. In [[Marfan syndrome]], the joints are very mobile, and similar cardiovascular complications occur. People with a "[[marfanoid]]" appearance are often tall and thin with long arms and legs and "spidery" fingers while EDS phenotypes vary considerably. Certain subtypes of EDS may involve short stature, large eyes, and the appearance of a small mouth and chin, due to a small palate. The palate can have a high arch, causing dental crowding. Blood vessels can sometimes be easily seen through translucent skin, especially on the chest. The genetic connective tissue disorder [[Loeys–Dietz syndrome]] also has symptoms that overlap with EDS.<ref>{{cite web|url=http://www.loeysdietz.org/en/medical-information/differential-diagnosis|title=Differential Diagnosis |website=www.loeysdietz.org|url-status=live|archive-url=https://web.archive.org/web/20170623074459/http://www.loeysdietz.org/en/medical-information/differential-diagnosis|archive-date=2017-06-23}}</ref>

In the past, [[Menkes disease]], a copper metabolism disorder, was thought to be a form of EDS. People are commonly misdiagnosed with [[fibromyalgia]], [[Coagulopathy|bleeding disorders]], or other disorders that can mimic EDS symptoms. Because of these similar disorders and complications that can arise from an unmonitored case of EDS, a correct diagnosis is important.<ref>{{cite web |url=http://rarediseases.about.com/cs/ehlersdanlossynd/a/102603.htm |title=Ehlers–Danlos Syndrome |publisher=Rarediseases.about.com |date=2006-05-25 |access-date=2014-02-27 |url-status=live |archive-url=https://web.archive.org/web/20140412011912/http://rarediseases.about.com/cs/ehlersdanlossynd/a/102603.htm |archive-date=2014-04-12}}</ref> [[Pseudoxanthoma elasticum]] is worth consideration in diagnosis.<ref>{{cite web|url=https://ghr.nlm.nih.gov/condition/pseudoxanthoma-elasticum|title=Pseudoxanthoma elasticum |website=Genetics Home Reference|access-date=2018-04-17}}</ref>