Editing Working memory (section)

===Alzheimer's disease===
As [[Alzheimer's disease]] becomes more serious, less working memory functions. In addition to deficits in [[episodic memory]], Alzheimer's disease is associated with impairments in visual short-term memory, assessed using delayed reproduction tasks.<ref>{{cite journal | vauthors = Zokaei N, Sillence A, Kienast A, Drew D, Plant O, Slavkova E, Manohar SG, Husain M | display-authors = 6 | title = Different patterns of short-term memory deficit in Alzheimer's disease, Parkinson's disease and subjective cognitive impairment | journal = Cortex; A Journal Devoted to the Study of the Nervous System and Behavior | volume = 132 | pages = 41–50 | date = November 2020 | pmid = 32919108 | pmc = 7651994 | doi = 10.1016/j.cortex.2020.06.016 }}</ref><ref>{{cite journal | vauthors = Liang Y, Pertzov Y, Nicholas JM, Henley SM, Crutch S, Woodward F, Leung K, Fox NC, Husain M | display-authors = 6 | title = Visual short-term memory binding deficit in familial Alzheimer's disease | journal = Cortex; A Journal Devoted to the Study of the Nervous System and Behavior | volume = 78 | pages = 150–164 | date = May 2016 | pmid = 27085491 | pmc = 4865502 | doi = 10.1016/j.cortex.2016.01.015 }}</ref><ref>{{cite book |doi=10.1007/7854_2019_103 |chapter=Working Memory in Alzheimer's Disease and Parkinson's Disease |title=Processes of Visuospatial Attention and Working Memory |series=Current Topics in Behavioral Neurosciences |date=2019 |last1=Zokaei |first1=Nahid |last2=Husain |first2=Masud |volume=41 |pages=325–344 |pmid=31347008 |isbn=978-3-030-31025-7 }}</ref> These investigations point to a deficit in visual feature binding as an important component of the deficit in Alzheimer's disease. There is one study that focuses on the neural connections and fluidity of working memory in mice brains. Half of the mice were given an injection that mimicked the effects of Alzheimer's, and the other half were not. Then the mice were expected to go through a maze that is a task to test working memory. The study helps answer questions about how Alzheimer's can deteriorate the working memory and ultimately obliterate memory functions.<ref>{{cite journal | vauthors = Liu T, Bai W, Yi H, Tan T, Wei J, Wang J, Tian X | title = Functional connectivity in a rat model of Alzheimer's disease during a working memory task | journal = Current Alzheimer Research | volume = 11 | issue = 10 | pages = 981–991 | date = December 2014 | pmid = 25387338 | doi = 10.2174/1567205011666141107125912 }}</ref>