Editing Spider silk (section)

== Research ==
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|+ Significant papers (50 or more citations)
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! scope="col" width="50pt" | Area of contribution

! scope="col" | Year

! scope="col" | Main researchers

! scope="col" | Title

! scope="col" | Contribution to the field
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! scope="row" rowspan="2" | Chemical Basis
| 1960 || Fischer, F. & Brander, J.<ref>{{cite journal |author= Fischer, F.|author2= Brander, J.|name-list-style= amp |date= 1960 |title= Eine Analyse der Gespinste der Kreuzspinne |journal= Hoppe-Seyler's Zeitschrift für Physiologische Chemie |volume= 320 |pages= 92–102 |doi=10.1515/bchm2.1960.320.1.92 |pmid= 13699837}}</ref> || "Eine Analyse der Gespinste der Kreuzspinne" (Amino acid composition analysis of spider silk) ||
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| 1960 || Lucas, F. et al.<ref>{{cite journal |author= Lucas, F.|author2= Shaw, J. T. B.|author3= Smith, S. G.|name-list-style= amp |date= 1960 |title= The Composition of Arthropod Silk Fibrons |journal= Insect Chemistry |volume= Symp. 3 |pages= 208–14 }}</ref><ref>{{cite journal |author= Lucas, F.|author2= Shaw, J. T. B.|author3= Smith, S. G.|name-list-style= amp |date= 1960 |title= Comparative studies of fibroins.I. The amino acid composition of various fibroins and its significance in relation to their crystal structure and taxonomy |journal= Journal of Molecular Biology |volume= 2 |pages= 339–49 |doi=10.1016/S0022-2836(60)80045-9|pmid=13763962 |issue= 6 }}</ref> || "The Composition of Arthropod Silk Fibroins; Comparative studies of fibroins" ||
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! scope="row" | Gene Sequence
| 1990 || Xu, M. & Lewis, R. V.<ref>{{cite journal |author= Xu, M.|author2= Lewis, R. V.|name-list-style= amp |date= 1990 |title= Structure of a Protein Superfiber – Spider Dragline Silk |journal= Proceedings of the National Academy of Sciences of the United States of America |volume= 87 |pages= 7120–24 |doi=10.1073/pnas.87.18.7120 |pmid= 2402494 |issue= 18 |pmc= 54695 |bibcode = 1990PNAS...87.7120X |doi-access= free}}</ref> || "Structure of a Protein Superfiber&nbsp;− Spider Dragline Silk" ||
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! scope="row" rowspan="4" | Mechanical Properties
| 1964 || Lucas, F.<ref>{{cite journal |author= Lucas, F. |date= 1964 |title= Spiders and their silks |journal= Discovery |volume= 25 |pages= 20–26 }}</ref> || "Spiders and their silks" || First time mechanical properties of spider silk compared with other materials in a scientific paper.
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| 1989 || Vollrath, F. & Edmonds, D. T.<ref>{{cite journal |author= Vollrath, F.|author2= Edmonds, D. T.|name-list-style= amp |date= 1989 |title= Modulation of the Mechanical-Properties of Spider Silk By Coating With Water |journal= Nature |volume= 340 |pages= 305–07 |doi= 10.1038/340305a0 |issue=6231|bibcode = 1989Natur.340..305V |s2cid= 4355740}}</ref> || "Modulation of the Mechanical Properties of Spider Silk by Coating with Water" || First important paper suggesting the water interplay with spider silk fibroin modulating silk properties.
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| 2001 || Vollrath, F. & Shao, Z.Z.<ref>{{cite journal |author= Vollrath, F.|author2= Madsen, B.|author3= Shao, Z. Z.|name-list-style= amp |date= 2001 |title= The effect of spinning conditions on the mechanics of a spider's dragline silk |journal= [[Proceedings of the Royal Society B]] |volume= 268 |pages= 2339–46 |doi=10.1098/rspb.2001.1590 |issue= 1483 |pmid=11703874 |pmc=1088885}}</ref> || "The effect of spinning conditions on the mechanics of a spider's dragline silk" ||
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| 2006 || Plaza, G.R., Guinea, G.V., Pérez-Rigueiro, J. & Elices, M.<ref name="plaza 06"/> || "Thermo-hygro-mechanical behavior of spider dragline silk: Glassy and rubbery states" || Combined effect of humidity and temperature on mechanical properties. Glass-transition temperature dependence on humidity.
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! scope="row" rowspan="7" | Structural Characterisation
| 1992 || Hinman, M.B. & Lewis, R. V<ref name="Hinman 92"/> || "Isolation of a clone encoding a second dragline silk fibroin. Nephila clavipes dragline silk is a two-protein fiber" ||
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| 1994 || Simmons, A. et al.<ref>{{cite journal |author= Simmons, A.|author2= Ray, E.|author3= Jelinski, L. W.|name-list-style= amp |date= 1994 |title= Solid-State C-13 NMR of Nephila-Clavipes Dragline Silk Establishes Structure and Identity of Crystalline Regions |journal= Macromolecules |volume= 27 |pages= 5235–37 |doi=10.1021/ma00096a060 |issue= 18 |bibcode = 1994MaMol..27.5235S }}</ref> || "Solid-State C-13 Nmr of Nephila-Clavipes Dragline Silk Establishes Structure and Identity of Crystalline Regions" || First NMR study of spider silk.
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| 1999 || Shao, Z., Vollrath, F. et al.<ref>{{cite journal |author= Shao, Z.|author2= Vollrath, F.|author3= Sirichaisit, J.|author4= Young, R. J.|name-list-style= amp |date= 1999 |title= Analysis of spider silk in native and supercontracted states using Raman spectroscopy |journal= Polymer |volume= 40 |pages= 2493–500 |doi=10.1016/S0032-3861(98)00475-3 |issue= 10 }}</ref> || "Analysis of spider silk in native and supercontracted states using Raman spectroscopy" || First Raman study of spider silk.
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| 1999 || Riekel, C., Muller, M.et al.<ref>{{cite journal |author= Riekel, C. |date= 1999 |title= Aspects of X-ray diffraction on single spider fibers |journal= Int. J. Biol. Macromol. |volume= 24 |pages= 179–86 |doi=10.1016/S0141-8130(98)00084-1 |pmid= 10342763 |last2= Bränden |first2= C |last3= Craig |first3= C |last4= Ferrero |first4= C |last5= Heidelbach |first5= F |last6= Müller |first6= M |issue= 2–3 }}</ref> || "Aspects of X-ray diffraction on single spider fibers" || First X-ray on single spider silk fibres.
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| 2000 || Knight, D.P., Vollrath, F. et al.<ref>{{cite journal |author= Knight, D. P.|author2= Knight, M. M.|author3= Vollrath, F.|name-list-style= amp |date= 2000 |title= Beta transition and stress-induced phase separation in the spinning of spider dragline silk |journal= Int. J. Biol. Macromol. |volume= 27 |pages= 205–10 |doi=10.1016/S0141-8130(00)00124-0 |pmid= 10828366 |issue= 3 }}</ref> || "Beta transition and stress-induced phase separation in the spinning of spider dragline silk" || Secondary structural transition confirmation during spinning.
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| 2001 || Riekel, C. & Vollrath, F.<ref>{{cite journal |author= Riekel, C.|author2= Vollrath, F.|name-list-style= amp |date= 2001 |title= Spider silk fibre extrusion: combined wide- and small-angle X- ray microdiffraction experiments |journal= Int. J. Biol. Macromol. |volume= 29 |pages= 203–10 |doi=10.1016/S0141-8130(01)00166-0 |pmid= 11589973 |issue= 3 }}</ref> || "Spider silk fibre extrusion: combined wide- and small-angle X- ray microdiffraction experiments" || First X-ray on spider silk dope.
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| 2002 || Van Beek, J. D. et al.<ref name="van Beek 02"/> || "The molecular structure of spider dragline silk: Folding and orientation of the protein backbone" ||
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! scope="row" rowspan="4" | Structure-Property Relationship
| 1986 || Gosline, G.M. et al.<ref>{{cite journal |author= Gosline, J. M.|author2= DeMont, M. E.|author3= Denny, M. W.|name-list-style= amp |date= 1986 |title= The structure and properties of spider silk |journal= Endeavour |volume= 10 |pages= 37–43 |doi=10.1016/0160-9327(86)90049-9 }}</ref> || "The structure and properties of spider silk" || First attempt to link structure with properties of spider silk
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| 1994 || Termonia, Y<ref name="Termonia 94"/> || "Molecular Modeling of Spider Silk Elasticity" || X-ray evidence presented in this paper; simple model of crystallites embedded in amorphous regions.
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| 1996 || Simmons, A. et al.<ref name="Simmons 96"/> || "Molecular orientation and two-component nature of the crystalline fraction of spider dragline silk" || Two types of alanine-rich crystalline regions were defined.
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| 2006 || Vollrath, F. & Porter, D.<ref>{{cite journal |author= Vollrath, F.|author2= Porter, D.|name-list-style= amp |date= 2006 |title= Spider silk as an archetypal protein elastomer |journal= Soft Matter |volume= 2 |pages= 377–85 |doi= 10.1039/b600098n |issue= 5|pmid= 32680251|bibcode = 2006SMat....2..377V |s2cid= 97234857}}</ref> || "Spider silk as an archetypal protein elastomer" || New insight and model to spider silk based on Group Interaction Modelling.
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! scope="row" rowspan="4" | Native Spinning
| 1991 || Kerkam, K., Kaplan, D. et al.<ref>{{cite journal |author= Kerkam, K.|author2= Viney, C.|author3= Kaplan, D.|author4= Lombardi, S.|name-list-style= amp |date= 1991 |title= Liquid Crystallinity of Natural Silk Secretions |journal= Nature |volume= 349 |pages= 596–98 |doi= 10.1038/349596a0 |issue=6310|bibcode = 1991Natur.349..596K |s2cid= 4348041}}</ref> || "Liquid Crystallinity of Natural Silk Secretions" ||
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| 1999 || Knight, D.P. & Vollrath, F.<ref>{{cite journal |author= Knight, D. P.|author2= Vollrath, F.|name-list-style= amp |date= 1999 |title= Liquid crystals and flow elongation in a spider's silk production line |journal= [[Proceedings of the Royal Society B]] |volume= 266 |pages= 519–23 |doi=10.1098/rspb.1999.0667 |issue= 1418 |pmc= 1689793 }}</ref> || "Liquid crystals and flow elongation in a spider's silk production line" ||
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| 2001 || Vollrath, F. & Knight, D.P.<ref name="Vollrath 01"/>|| "Liquid crystalline spinning of spider silk" || Most cited spider silk paper
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| 2005 || Guinea, G.V., Elices, M., Pérez-Rigueiro, J. & Plaza, G.R.<ref name="guinea 05"/> || "Stretching of supercontracted fibers: a link between spinning and the variability of spider silk" || Explanation of the variability of mechanical properties.
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! scope="row" rowspan="3" | Reconstituted /Synthetic Spider Silk and Artificial Spinning
| 1995 || Prince, J. T., Kaplan, D. L. et al.<ref>{{cite journal |author= Prince, J. T.|author2= McGrath, K. P.|author3= Digirolamo, C. M.|author4= Kaplan, D. L. |author4-link=David L. Kaplan (engineer) |name-list-style= amp |date= 1995 |title= Construction, Cloning, and Expression of Synthetic Genes Encoding Spider Dragline Silk |journal= Biochemistry |volume= 34 |pages= 10879–85 |doi=10.1021/bi00034a022 | pmid=7662669 |issue= 34 }}</ref> || "Construction, Cloning, and Expression of Synthetic Genes Encoding Spider Dragline Silk" || First successful synthesis of Spider silk by ''E. coli''.
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| 1998 || Arcidiacono, S., Kaplan, D.L. et al.<ref>{{cite journal |author= Arcidiacono, S.|author2= Mello, C.|author3= Kaplan, D.|author4= Cheley, S.|author5= Bayley, H.|name-list-style= amp |date= 1998 |title= Purification and characterization of recombinant spider silk expressed in Escherichia coli |journal= Applied Microbiology and Biotechnology |volume= 49 |pages= 31–38 |doi= 10.1007/s002530051133| pmid=9487707 |issue= 1 |s2cid= 35267049}}</ref> || "Purification and characterization of recombinant spider silk expressed in Escherichia coli" ||
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| 1998 || Seidel, A., Jelinski, L.W. et al.<ref>{{cite journal |author= Seidel, A.|author2= Liivak, O.|author3= Jelinski, L. W.|name-list-style= amp |date= 1998 |title= Artificial Spinning of Spider Silk |journal= Macromolecules |volume= 31 |pages= 6733–36 |doi=10.1021/ma9808880 |issue= 19 |bibcode = 1998MaMol..31.6733S }}</ref> || "Artificial Spinning of Spider Silk" || First controlled wet-spinning of reconstituted spider silk.
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