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==Epidemiology== {{Globalize|section|date=August 2016}} The Wisconsin Sleep Cohort Study estimated in 1993 that roughly one in every 15 Americans was affected by at least moderate sleep apnea.<ref name="pmid8464434" /><ref name="pmid19690624" /> It also estimated that in middle-age as many as 9% of women and 24% of men were affected, undiagnosed and untreated.<ref name="young"/><ref name="pmid8464434">{{cite journal |last1=Young |first1=Terry |last2=Palta |first2=Mari |last3=Dempsey |first3=Jerome |last4=Skatrud |first4=James |last5=Weber |first5=Steven |last6=Badr |first6=Safwan |title=The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults |journal=New England Journal of Medicine |date=29 April 1993 |volume=328 |issue=17 |pages=1230β1235 |doi=10.1056/NEJM199304293281704 |pmid=8464434 |s2cid=9183654 |doi-access=free }}</ref><ref name="pmid19690624">{{cite journal | vauthors = Lee W, Nagubadi S, Kryger MH, Mokhlesi B | title = Epidemiology of Obstructive Sleep Apnea: a Population-based Perspective | journal = Expert Review of Respiratory Medicine | volume = 2 | issue = 3 | pages = 349β364 | date = June 2008 | pmid = 19690624 | pmc = 2727690 | doi = 10.1586/17476348.2.3.349 }}</ref> The costs of untreated sleep apnea reach further than just health issues. It is estimated that in the U.S., the average untreated sleep apnea patient's annual health care costs $1,336 more than an individual without sleep apnea. This may cause $3.4 billion/year in additional medical costs. Whether medical cost savings occur with treatment of sleep apnea remains to be determined.<ref>{{cite journal |last1=Kapur |first1=Vishesh |last2=Blough |first2=David K. |last3=Sandblom |first3=Robert E. |last4=Hert |first4=Richard |last5=de Maine |first5=James B. |last6=Sullivan |first6=Sean D. |last7=Psaty |first7=Bruce M. |title=The Medical Cost of Undiagnosed Sleep Apnea |journal=Sleep |date=September 1999 |volume=22 |issue=6 |pages=749β755 |doi=10.1093/sleep/22.6.749 |pmid=10505820 |doi-access=free }}</ref>
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