Editing Syphilis (section)

===Secondary===
[[Image:Secondary Syphilis on palms CDC 6809 lores.rsh.jpg|thumb|upright=1.4|Typical presentation of secondary syphilis with a rash on the palms of the hands, 1967]]
[[image:Syphilis second state 2.jpg|thumb|upright=1.4|Reddish [[papules]] and [[nodule (dermatology)#Primary lesions|nodules]] over much of the body due to secondary syphilis]]
Secondary syphilis occurs approximately four to ten weeks after the primary infection.<ref name=Kent08/> While secondary disease is known for the many different ways it can manifest, symptoms most commonly involve the [[Human skin|skin]], [[mucous membranes]], and [[lymph nodes]].<ref name=Sec2010/> There may be a symmetrical, reddish-pink, non-itchy [[rash]] on the trunk and extremities, including the palms and soles.<ref name=Kent08/><ref name=2darySyphilis>{{cite journal |vauthors=Dylewski J, Duong M |title=The rash of secondary syphilis |journal=Canadian Medical Association Journal |date= 2 January 2007 |volume=176 |issue=1 |pages=33–35 |doi= 10.1503/cmaj.060665 |pmid=17200385 |pmc=1764588}}</ref> The rash may become [[maculopapular]] or [[abscess|pustular]].<ref name=Kent08/> It may form flat, broad, whitish, wart-like lesions on mucous membranes, known as [[condyloma latum]].<ref name=Kent08/> All of these lesions harbor bacteria and are infectious.<ref name=Kent08/> Other symptoms may include [[fever]], [[sore throat]], [[malaise]], [[weight loss]], [[hair loss]], and [[headache]].<ref name=Kent08/> Rare manifestations include [[hepatitis|liver inflammation]], [[kidney]] disease, [[arthritis|joint inflammation]], [[periostitis]], [[optic neuritis|inflammation of the optic nerve]], [[uveitis]], and [[interstitial keratitis]].<ref name=Kent08/><ref name=Eye07/> The acute symptoms usually resolve after three to six weeks;<ref name=Eye07/> about 25% of people may present with a recurrence of secondary symptoms.<ref name=Sec2010/><ref>{{cite journal |last1=Baughn |first1=R. E. |last2=Musher |first2=D. M. |title=Secondary Syphilitic Lesions |journal=Clinical Microbiology Reviews |date=14 January 2005 |volume=18 |issue=1 |pages=205–16 |doi=10.1128/CMR.18.1.205-216.2005|pmid=15653827 |pmc=544174 }}</ref> Many people who present with secondary syphilis (40–85% of women, 20–65% of men) do not report previously having had the classical chancre of primary syphilis.<ref name=Sec2010>{{cite journal |last=Mullooly|first=C|author2=Higgins, SP |title=Secondary syphilis: the classical triad of skin rash, mucosal ulceration and lymphadenopathy|journal=International Journal of STD & AIDS|date=August 2010|volume=21|issue=8|pages=537–45|pmid=20975084|doi=10.1258/ijsa.2010.010243|s2cid=207198662}}</ref>