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Salicylic acid
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===Uses in manufacturing=== Salicylic acid is used as a [[food preservative]], a [[bactericide]], and an [[antiseptic]].<ref name=mnet>{{cite web|url=http://www.medterms.com/script/main/art.asp?articlekey=25386|title=Definition of Salicylic acid|website=MedicineNet.com|access-date=2010-10-12|archive-url=https://web.archive.org/web/20111209055454/http://www.medterms.com/script/main/art.asp?articlekey=25386|archive-date=2011-12-09|url-status=live}}</ref><ref name="greene13">{{cite book | vauthors = Greene SA |title=Sittig's Handbook of Pesticides and Agricultural Chemicals |date=2013 |publisher=William Andrew |isbn=978-0-8155-1903-4 |url=https://books.google.com/books?id=hAoKEHpyu6wC&pg=PA778}}</ref> Salicylic acid is used in the production of other pharmaceuticals, including [[4-aminosalicylic acid]], [[sulpiride|sandulpiride]], and landetimide (via salethamide).<ref>{{cite web |title=Medicines containing the active ingredient salicylic acid - (emc) |url=https://www.medicines.org.uk/emc/ingredient/13#gref |access-date=2022-10-23 |website=www.medicines.org.uk}}</ref> It is also used in [[picric acid]] production.<ref>{{Cite web |title=λ » LambdaSyn – Synthese von Pikrinsäure |url=https://www.lambdasyn.org/synfiles/pikrinsaeure.htm |access-date=2024-08-01 |website=www.lambdasyn.org}}</ref> Salicylic acid has long been a key starting material for making [[acetylsalicylic acid]] (ASA or aspirin).<ref name=Ullmann/> ASA is prepared by the [[acetylation]] of salicylic acid with the acetyl group from [[acetic anhydride]] or [[acetyl chloride]].<ref>{{cite book |last1=Watson |first1=David G |title=Pharmaceutical chemistry |date=2011 |publisher=Churchill Livingstone |location=Edinburgh |isbn=978-0-7020-4850-0 |page=273 |url=https://books.google.com/books?id=-lQM4xHjWeUC |access-date=21 May 2022}}</ref> ASA is the standard to which all the other non-steroidal anti-inflammatory drugs ([[NSAID]]s) are compared. In veterinary medicine, this group of drugs is mainly used for treatment of inflammatory musculoskeletal disorders.<ref name="emea99">{{cite news |title=ACETYLSALICYLIC ACID, SODIUM ACETYLSALICYLATE, ACETYLSALICYLIC ACID DL-LYSINE AND CARBASALATE CALCIUM SUMMARY REPORT |url=https://www.ema.europa.eu/en/documents/mrl-report/acetylsalicylic-acid-sodium-acetylsalicylate-acetylsalicylic-acid-dl-lysine-carbasalate-calcium_en.pdf |agency=The European Agency for the Evaluation of Medicinal Products Veterinary Medicines and Inspections |issue=EMEA/MRL/695/99–FINAL |publisher=COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS |date=November 1999}}</ref> [[Bismuth subsalicylate]], a [[salt (chemistry)|salt]] of [[bismuth]] and salicylic acid, "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".<ref name="pubchem" /> It is an active ingredient in stomach-relief aids such as [[Pepto-Bismol]] and some formulations of [[Kaopectate]]. Other derivatives include [[methyl salicylate]], used as a [[liniment]] to soothe joint and muscle pain, and [[choline salicylate]], which is used topically to relieve the pain of [[aphthous ulcer|mouth ulcers]].<ref name=pubchem/><ref name=drugs/><ref>{{cite journal |last1=Wróblewska |first1=Katarzyna B. |last2=Plewa |first2=Szymon |last3=Dereziński |first3=Paweł |last4=Muszalska-Kolos |first4=Izabela |title=Choline Salicylate Analysis: Chemical Stability and Degradation Product Identification |journal=Molecules |date=22 December 2019 |volume=25 |issue=1 |pages=51 |doi=10.3390/molecules25010051|pmid=31877863 |pmc=6983192 |doi-access=free }}</ref> [[Aminosalicylic acid]] is used to induce remission in [[ulcerative colitis]], and has been used as an [[antitubercular agent]] often administered in association with [[isoniazid]].<ref name="drugbank1">{{cite web |title=Aminosalicylic acid |url=https://go.drugbank.com/drugs/DB00233 |website=Drugbank Online}}</ref> [[Sodium salicylate]] is a useful [[phosphor]] in the [[vacuum ultraviolet]] spectral range, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm.<ref name=samson76>Samson, James (1976). ''Techniques of Vacuum Ultraviolet Spectroscopy''. Wiley, .</ref> It fluoresces in the blue at 420 nm. It is easily prepared on a clean surface by spraying a saturated solution of the salt in [[methanol]] followed by evaporation.{{citation needed|date=December 2021}}
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