Editing Marfan syndrome (section)

===Eyes===
[[File:Lens marfan.gif|thumb|[[Lens dislocation]] in Marfan syndrome with the lens being kidney-shaped and resting against the [[ciliary body]]]]
In Marfan syndrome, the health of the eye can be affected in many ways, but the principal change is partial [[ectopia lentis|lens dislocation]], where the lens is shifted out of its normal position.<ref name=":1" /> This occurs because of weakness in the [[zonule of Zinn|ciliary zonules]], the connective tissue strands which suspend the lens within the eye. The mutations responsible for Marfan syndrome weaken the zonules and cause them to stretch. The inferior zonules are most frequently stretched resulting in the lens shifting upwards and outwards, but it can shift in other directions as well. [[Myopia|Nearsightedness]] (myopia), and [[astigmatism (eye)|blurred vision]] are common due to connective tissue defects in the eye.<ref name=":3">{{cite web|url=https://www.genome.gov/Genetic-Disorders/Marfan-Syndrome|title=About Marfan Syndrome|website=Genome.gov|language=en|access-date=2020-03-02|archive-date=2020-03-02|archive-url=https://web.archive.org/web/20200302201425/https://www.genome.gov/Genetic-Disorders/Marfan-Syndrome|url-status=live}}</ref> Farsightedness can also result particularly if the lens is highly subluxated. [[Ectopia lentis|Subluxation]] (partial dislocation) of the [[lens (anatomy)|lens]] can be detected clinically in about 60% of people with Marfan syndrome by the use of a [[Slit lamp|slit-lamp]] biomicroscope.<ref name=":3" /> If the lens subluxation is subtle, then imaging with high-resolution ultrasound biomicroscopy might be used.<ref>{{Cite journal |last1=Liu |first1=Yi-Zhi |last2=Liu |first2=Yu-Hua |last3=Wu |first3=Ming-Xing |last4=Luo |first4=Li-Xia |last5=Zhang |first5=Xin-Yu |last6=Cai |first6=Xiao-Yu |last7=Chen |first7=Xiu-Qi |date=March 2004 |title=[Clinical applications of ultrasound biomicroscopy in diagnosis and treatment of lens subluxation] |url=https://pubmed.ncbi.nlm.nih.gov/15307991/ |journal=[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology |volume=40 |issue=3 |pages=186–189 |issn=0412-4081 |pmid=15307991 |access-date=2022-10-09 |archive-date=2022-10-09 |archive-url=https://web.archive.org/web/20221009080041/https://pubmed.ncbi.nlm.nih.gov/15307991/ |url-status=live }}</ref>

Other signs and symptoms affecting the eye include increased length along an axis of the globe, myopia, corneal flatness, [[strabismus]], [[exotropia]], and [[esotropia]].<ref name=":1" /> Those with MFS are also at a high risk for early [[glaucoma]] and early [[cataract]]s.<ref name=":3" />