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==Classification of tuberculin reaction== The results of this test must be interpreted carefully. The person's medical risk factors determine at which increment (5 mm, 10 mm, or 15 mm) of induration the result is considered positive.<ref>From the CDC team of the CDC team at the Saskatchewan Lung Association, [http://www.lung.ca/tb/tbtoday/tbdiagnosis/skin_test.html photos of a PPD bump] {{webarchive|url=https://web.archive.org/web/20070321005807/http://www.lung.ca/tb/tbtoday/tbdiagnosis/skin_test.html |date=2007-03-21 }}.</ref> A positive result indicates TB exposure. * 5 mm or more is positive in ** An HIV-positive person ** Persons with recent contacts with a TB patient ** Persons with nodular or fibrotic changes on chest X-ray consistent with old healed TB ** Patients with organ transplants, and other immunosuppressed patients * 10 mm or more is positive in ** Recent arrivals (less than five years) from [[Tuberculosis#Epidemiology|high-prevalence countries]] ** Injection drug users ** Residents and employees of high-risk congregate settings (e.g., prisons, nursing homes, hospitals, homeless shelters, etc.) ** [[Mycobacteria|Mycobacteriology]] lab personnel ** Persons with clinical conditions that place them at high risk (e.g., [[diabetes]], prolonged [[corticosteroid]] therapy, [[leukemia]], [[renal failure|end-stage renal disease]], chronic [[malabsorption]] syndromes, low body weight, etc.) ** Children less than four years of age, or children and adolescents exposed to adults in high-risk categories * 15 mm or more is positive in ** Persons with no known risk factors for TB<ref>[http://www.eac.int/health/index.php?option=com_content&id=79%3Aclassification-system&Itemid=34 Mantoux Test] {{Webarchive|url=https://web.archive.org/web/20160930155812/http://www.eac.int/health/index.php?option=com_content&id=79%3Aclassification-system&Itemid=34 |date=2016-09-30 }} in eac.int.</ref> A tuberculin test conversion is defined as an increase of 10 mm or more within a two-year period, regardless of age. Alternative criteria include increases of 6, 12, 15 or 18 mm.<ref name="pmid9872812">{{cite journal|last=Menzies|first=Dick|title=Interpretation aof Repeated Tuberculin Tests|journal=American Journal of Respiratory and Critical Care Medicine|date=1 January 1999|volume=159|issue=1|pages=15β21|doi=10.1164/ajrccm.159.1.9801120|pmid=9872812}}</ref>
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