Editing Ketosis (section)

===Ketoacidosis===
[[Ketoacidosis]] is a pathological state of uncontrolled production of ketones that results in a [[metabolic acidosis]], with serum ketone levels typically in excess of 3&nbsp;mM. Ketoacidosis is most commonly caused by a deficiency of insulin in type 1 diabetes or late stage type 2 diabetes but can also be the result of chronic heavy alcohol use, [[salicylate poisoning]], or isopropyl alcohol ingestion.<ref name=":6" /><ref name=":4" /> Ketoacidosis causes significant metabolic derangements and is a life-threatening medical emergency.<ref name=":4" /> Ketoacidosis is distinct from physiological ketosis as it requires failure of the normal regulation of ketone body production.<ref name=":9">{{cite journal |last1=Krebs |first1=H.A. |title=The regulation of the release of ketone bodies by the liver |journal=Advances in Enzyme Regulation |date=January 1966 |volume=4 |pages=339–353 |doi=10.1016/0065-2571(66)90027-6 |pmid=4865971 }}</ref><ref name=":5" />