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===Pregnancy=== {{Main|Thyroid disease in women}} Hypothyroidism when untreated may lead to [[infertility]] and an increased risk of [[miscarriage]] or [[perinatal mortality|infant death around the time of birth]], mostly in severe cases of hypothyroidism.<ref name=NIH2017>{{cite web|title=Thyroid disease in Women|url=https://www.niddk.nih.gov/health-information/endocrine-diseases/pregnancy-thyroid-disease|publisher=Office on Women's Health, U.S. Department of Health and Human Services|access-date=15 March 2025|date=December 2017|url-status=live|archive-url=https://web.archive.org/web/20250304231739/https://www.niddk.nih.gov/health-information/endocrine-diseases/pregnancy-thyroid-disease|archive-date=4 March 2025}}{{PD-notice}}</ref><ref>{{cite web | title =Postpartum Thyroiditis | publisher = American Thyroid Association | access-date = 20 July 2017 | date = 2014| url = http://www.thyroid.org/wp-content/uploads/patients/brochures/Postpartum_Thyroiditis_brochure.pdf}}</ref> [[Thyroid disease in pregnancy|Women are affected by hypothyroidism]] in 0.3β0.5% of pregnancies.<ref name=Vissenberg2012>{{cite journal | vauthors = Vissenberg R, van den Boogaard E, van Wely M, van der Post JA, Fliers E, Bisschop PH, Goddijn M | title = Treatment of thyroid disorders before conception and in early pregnancy: a systematic review | journal = Human Reproduction Update | volume = 18 | issue = 4 | pages = 360β73 | date = July 2012 | pmid = 22431565 | doi = 10.1093/humupd/dms007 | type = Review | doi-access = free }}</ref> Subclinical hypothyroidism during pregnancy is associated with [[preterm birth|birth of the baby before 37 weeks of pregnancy]].<ref>{{cite journal | vauthors = Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S | title = 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum | journal = Thyroid | volume = 27 | issue = 3 | pages = 315β389 | date = March 2017 | pmid = 28056690 | doi = 10.1089/thy.2016.0457 | pmc = 3472679 | doi-access = free }}</ref>
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