Editing Hypothalamus (section)

===Connections===
{{Further|Lateral hypothalamus#Orexinergic projection system|Tuberomammillary nucleus#Histaminergic outputs}}
The hypothalamus is highly interconnected with other parts of the [[central nervous system]], in particular the brainstem and its [[reticular formation]]. As part of the [[limbic system]], it has connections to other limbic structures including the [[amygdala]] and [[septum]], and is also connected with areas of the [[autonomous nervous system]]. {{cn|date=March 2025}}

The hypothalamus receives many inputs from the [[brainstem]], the most notable from the [[nucleus of the solitary tract]], the [[locus coeruleus]], and the [[ventrolateral medulla]]. {{cn|date=March 2025}}

'''Most''' nerve fibres within the hypothalamus run in two ways (bidirectional).
* Projections to areas [[Anatomical terms of location|caudal]] to the hypothalamus go through the [[medial forebrain bundle]], the [[mammillotegmental fasciculus|mammillotegmental tract]] and the [[dorsal longitudinal fasciculus]].
* Projections to areas rostral to the hypothalamus are carried by the [[mammillothalamic tract]], the [[Fornix of brain|fornix]] and [[terminal stria]].
* Projections to areas of the [[sympathetic nervous system|sympathetic motor system]] ([[lateral horn of spinal cord|lateral horn]] spinal segments T1–L2/L3) are carried by the [[hypothalamospinal tract]] and they activate the sympathetic motor pathway.