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===Placental mammals=== During gestation in [[placentalia|placental mammals]], there is a gradual physiological increase in [[senescence]] in the maternal [[decidua]] (the specialized layer of [[endometrium]] that forms the base of the placental bed) and in [[placenta]]l cells.<ref name = Singh2024>{{cite journal |vauthors=Singh VP, Singh P |title=Linking DNA damage and senescence to gestation period and lifespan in placental mammals |journal=Front Cell Dev Biol |volume=12 |issue= |pages=1480695 |date=2024 |pmid=39403126 |pmc=11471632 |doi=10.3389/fcell.2024.1480695 |doi-access=free |url=}}{{Creative Commons text attribution notice|cc=by4|from this source=yes}}</ref> This increase in senescence is associated with a gradual physiological increase in [[DNA damage (naturally occurring)|DNA damage]] during gestation. A positive correlation between the gestation period and maximum lifespan was observed across 740 mammalian species.<ref name = Singh2024/> It was postulated that the rates of DNA damage and senescence may impact the gestation period as well as lifespan.<ref name = Singh2024/>
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