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===Main=== [[File:FrazierCap.theora.ogv|thumb|Grammer, Hyde Pierce and Mahoney in character in an advertisement for [[US Treasury bonds]]|alt=]] * [[Kelsey Grammer]] as [[Frasier Crane]], a radio psychiatrist. He is fussy, uptight, cultured, and sometimes arrogant. Having grown up with an educated mother and an "[[average Joe]]" father, Frasier epitomizes an [[Upper class|upper-class]] sophistication, yet is still sympathetic to [[Working class|working-class]] culture. After returning to Seattle, he begins embracing his more privileged background and develops a more selfish and aloof manner, possibly due to rekindling his relationship with his younger brother, [[Niles Crane]]. Despite his haughty demeanor, however, Frasier has a strong sense of ethics. * [[Jane Leeves]] as [[Daphne Moon]] (later Crane), is an English immigrant from [[Manchester]]; a physiotherapist and live-in aid hired by Frasier to help his father. Daphne's eccentric, working-class background and self-professed psychic abilities (which often end up being correct) frequently lead to Daphne's comical non-sequiturs about her unusual family, which is a sharp contrast to the Cranes' incredulity. In spite of their different upbringings, Niles falls for her instantly. Niles's obsession with Daphne and her obliviousness to this is developed throughout the earlier seasons of the series. * [[David Hyde Pierce]] as [[Niles Crane]], Frasier's younger brother. He is a psychiatrist in private practice. Educated, coldhearted, and more arrogant than Frasier, Niles's snobby, anxious qualities provide a foil for Frasier's own issues. Despite his aforementioned qualities, he is brave, caring, and well-meaning, which, to his loved ones, more than makes up for his eccentricities and quirks. Niles is very close to his older brother, though their fiercely competitive natures often provide the audience with much humor throughout the series. Like Frasier, Niles has a deep appreciation and respect for the arts, music, and pursuits that are seen as intellectual and prefers these activities over most sports, though he excels in squash and croquet. Niles is severely [[mysophobia|mysophobic]], often given to wiping his hands after human contact, and is even depicted wiping down chairs in public places before sitting on them. * [[Peri Gilpin]] as [[Roz Doyle]], the producer of Frasier's radio show. A native of Bloomer, Wisconsin, Roz, one of two single women in the series, is depicted as a sharp contrast to Daphne. Throughout the show, Roz's search for love and liberal approach to dating is the subject of many witty remarks, particularly from Niles. In the middle of series' run, Roz becomes pregnant with her first child, Alice, and the show addresses some of the challenges of being a single mother, including Roz having to borrow money from her boss, and the personal and professional strain that places on their relationship. * [[John Mahoney]] as [[Martin Crane]], Frasier and Niles's father, is an outspoken and laid-back Seattle police detective who was forced to retire after sustaining a gunshot wound to his hip. Because this injury renders him incapable of living alone, upon Frasier's return to Seattle, Martin is forced to accept Frasier's invitation to live with him. Though he and his sons share few commonalities, the relationship between the three men strengthens throughout the series. Martin's relationship with his Jack Russell terrier, Eddie, and his pea-green tartan- and twill-upholstered recliner are a perpetual source of distress for Frasier. He is also known for his fondness for beer (specifically that for [[P. Ballantine and Sons Brewing Company|Ballantine]]). * [[Dan Butler]] as Bob "Bulldog" Briscoe (main seasons 4β6; recurring season 1; special appearance seasons 2β3; special guest seasons 7β11), the [[Lothario|womanizing]], [[Misogyny|misogynistic]] host of ''Bob "Bulldog" Briscoe and the Gonzo Sports Show'', which follows Frasier's time slot at KACL.
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