Editing Dermatitis (section)

===Complications===
People with eczema should not receive the [[Smallpox vaccine|smallpox vaccination]] due to risk of developing [[eczema vaccinatum]], a potentially severe and sometimes fatal complication.<ref>{{cite web |url= http://emergency.cdc.gov/agent/smallpox/vaccination/contraindications-clinic.asp |title=CDC Smallpox &#124; Smallpox (Vaccinia) Vaccine Contraindications (Info for Clinicians) |publisher=Emergency.cdc.gov |date=7 February 2007 |access-date=7 February 2010 |url-status=dead |archive-url=https://web.archive.org/web/20100125041841/http://emergency.cdc.gov/agent/smallpox/vaccination/contraindications-clinic.asp |archive-date=25 January 2010  }}</ref> Other major health risks for people with dermatitis are viral and bacterial infections because atopic dermatitis patients have deficiencies in their proteins and [[lipid]]s that have barrier functions along with defects in [[dendritic cell]]s and as a result are unable to keep foreign invaders out, leading to recurring infections.<ref name="Wang et al 2021">{{cite journal | vauthors = Wang V, Boguniewicz J, Boguniewicz M, Ong PY | title = The infectious complications of atopic dermatitis | journal = Annals of Allergy, Asthma & Immunology | volume = 126 | issue = 1 | pages = 3–12 | date = January 2021 | pmid = 32771354 | pmc = 7411503 | doi = 10.1016/j.anai.2020.08.002 }}</ref> If left untreated, these infections may be life-threatening, so skin barrier improvement (such as daily moisturizing to minimize [[transepidermal water loss]]) and anti-inflammatory therapy are recommended as preventative measures.<ref name="Wang et al 2021"/>