Editing Bactericide (section)

==Antibiotics==
Bactericidal [[antibiotic]]s kill bacteria; [[bacteriostatic]] antibiotics slow their growth or reproduction.

Bactericidal antibiotics that inhibit cell wall synthesis: the [[beta-lactam antibiotics]] ([[penicillin]] derivatives ([[penam]]s), [[cephalosporin]]s ([[cephem]]s), [[monobactam]]s, and [[carbapenem]]s) and [[vancomycin]].

Also bactericidal are [[daptomycin]], [[fluoroquinolone]]s, [[metronidazole]], [[nitrofurantoin]], [[co-trimoxazole]], [[telithromycin]].

[[Aminoglycoside|Aminoglycosidic antibiotics]]  are usually considered bactericidal, although they may be bacteriostatic with some organisms.

As of 2004, the distinction between bactericidal and bacteriostatic agents appeared to be clear according to the basic/clinical definition, but this only applies under strict laboratory conditions and it is important to distinguish microbiological and clinical definitions.<ref>{{cite journal
|title=Clinical Relevance of Bacteriostatic versus Bactericidal Mechanisms of Action in the Treatment of Gram-Positive Bacterial Infections 
|journal=Clin Infect Dis 
|year=2004
|volume=38
|issue=6
|pages=864–870
|doi=10.1086/381972
|pmid=14999632 | last1 = Pankey | first1 = GA | last2 = Sabath | first2 = LD|doi-access=free}}</ref> The distinction is more arbitrary when agents are categorized in clinical situations. The supposed superiority of bactericidal agents over bacteriostatic agents is of little relevance when treating the vast majority of infections with [[gram-positive bacteria]], particularly in patients with uncomplicated infections and noncompromised immune systems. Bacteriostatic agents have been effectively used for treatment that are considered to require bactericidal activity. Furthermore, some broad classes of antibacterial agents considered bacteriostatic can exhibit bactericidal activity against some bacteria on the basis of in vitro determination of MBC/MIC values. At high concentrations, bacteriostatic agents are often bactericidal against some susceptible organisms. The ultimate guide to treatment of any infection must be clinical outcome.