Editing Atropine (section)

=== Heart ===
[[Injection (medicine)|Injection]]s of atropine are used in the treatment of symptomatic or unstable [[bradycardia]].

Atropine was previously included in international resuscitation guidelines for use in cardiac arrest associated with [[asystole]] and [[pulseless electrical activity|PEA]] but was removed from these guidelines in 2010 due to a lack of evidence for its effectiveness.<ref>{{cite journal | vauthors = Field JM, Hazinski MF, Sayre MR, Chameides L, Schexnayder SM, Hemphill R, Samson RA, Kattwinkel J, Berg RA, Bhanji F, Cave DM, Jauch EC, Kudenchuk PJ, Neumar RW, Peberdy MA, Perlman JM, Sinz E, Travers AH, Berg MD, Billi JE, Eigel B, Hickey RW, Kleinman ME, Link MS, Morrison LJ, O'Connor RE, Shuster M, Callaway CW, Cucchiara B, Ferguson JD, Rea TD, Vanden Hoek TL | title = Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care | journal = Circulation | volume = 122 | issue = 18 Suppl 3 | pages = S640-56 | date = November 2010 | pmid = 20956217 | doi = 10.1161/CIRCULATIONAHA.110.970889 | s2cid = 1031566 | doi-access =  }}</ref>  For symptomatic bradycardia, the usual dosage is 0.5 to 1&nbsp;mg IV push; this may be repeated every 3 to 5 minutes, up to a total dose of 3&nbsp;mg (maximum 0.04&nbsp;mg/kg).<ref>* {{cite book | vauthors = Bledsoe BE, Porter RS, Cherry RA | year = 2004| title =  Intermediate Emergency Care | chapter = Ch. 3| page = 260 | publisher = Pearson Prentice Hill| location =Upper Saddle River, NJ | isbn = 0-13-113607-0}}</ref>

Atropine is also useful in treating [[Second-degree AV block#Types|second-degree heart block Mobitz type 1 (Wenckebach block)]], and also [[Third-degree AV block|third-degree heart block]] with a high [[Purkinje fibers|Purkinje]] or [[Atrioventricular node|AV-nodal]] [[escape rhythm]].  It is usually not effective in [[Second degree AV block#Type 2 Second-degree AV block|second-degree heart block Mobitz type 2]], and in [[Third-degree AV block|third-degree heart block]] with a low Purkinje or ventricular escape rhythm.{{citation needed|date=January 2022}}

Atropine has also been used to prevent a low heart rate during [[intubation]] of children; however, the evidence does not support this use.<ref>{{cite journal | vauthors = de Caen AR, Berg MD, Chameides L, Gooden CK, Hickey RW, Scott HF, Sutton RM, Tijssen JA, Topjian A, van der Jagt ÉW, Schexnayder SM, Samson RA | title = Part 12: Pediatric Advanced Life Support: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care | journal = Circulation | volume = 132 | issue = 18 Suppl 2 | pages = S526-42 | date = November 2015 | pmid = 26473000 | pmc = 6191296 | doi = 10.1161/cir.0000000000000266 }}</ref>